Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720147 | 0.90 | F2R (0.51) | F2RCNR1TMEM97HRH3HSD11B1 | |
| SCHEMBL13808164 | 0.83 | F2R (0.51) | F2RCNR1TMEM97HRH3TRPA1 | |
| SCHEMBL11997352 | 0.81 | F2R (0.49) | F2RCNR1TMEM97HSD11B1KCNH2 | |
| SCHEMBL10278640 | 0.79 | F2R (0.45) | F2RCNR1TMEM97TRPA1ALDH1A1 | |
| SCHEMBL11997340 | 0.79 | F2R (0.50) | F2RCNR1TMEM97HSD11B1TRPA1 | |
| SCHEMBL12720043 | 0.78 | F2R (0.53) | F2RCNR1TMEM97HRH3KCNH2 | |
| SCHEMBL12720313 | 0.78 | F2R (0.53) | F2RCNR1TMEM97 | |
| SCHEMBL10278573 | 0.77 | F2R (0.63) | F2RCNR1TMEM97HSD11B1TRPA1 | |
| SCHEMBL12720135 | 0.77 | F2R (0.52) | F2RCNR1TMEM97HRH3TRPA1 | |
| SCHEMBL10278942 | 0.77 | F2R (0.43) | F2RTRPC6ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |