Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 5/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13808164 | 0.94 | F2R (0.51) | F2RCNR1TMEM97EPHX2DPP4 | |
| SCHEMBL12720198 | 0.90 | F2R (0.40) | F2RCNR1TMEM97KCNH2MCHR1 | |
| SCHEMBL12720043 | 0.89 | F2R (0.53) | F2RCNR1TMEM97EPHX2MGLL | |
| SCHEMBL12720313 | 0.88 | F2R (0.53) | F2RCNR1TMEM97EPHX2 | |
| SCHEMBL12720135 | 0.87 | F2R (0.52) | F2RCNR1TMEM97EPHX2MGLL | |
| SCHEMBL641289 | 0.85 | F2R (0.59) | F2RCNR1TMEM97EPHX2MGLL | |
| SCHEMBL12720052 | 0.85 | F2R (0.49) | F2RCNR1TMEM97EPHX2MGLL | |
| SCHEMBL12720577 | 0.84 | F2R (0.51) | F2RCNR1TMEM97EPHX2MGLL | |
| SCHEMBL12720191 | 0.83 | F2R (0.55) | F2RCNR1TMEM97EPHX2KCNH2 | |
| SCHEMBL642302 | 0.82 | F2R (0.62) | F2RCNR1TMEM97EPHX2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |