Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720266 | 0.92 | F2R (0.49) | F2R | |
| SCHEMBL12720061 | 0.90 | F2R (0.51) | F2RRAB9ANPC1GRM5KMT2A | |
| SCHEMBL12720549 | 0.89 | F2R (0.57) | F2RRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12720557 | 0.87 | F2R (0.48) | F2RUSP2 | |
| SCHEMBL640480 | 0.86 | RAB9A (0.57) | F2RRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12720254 | 0.84 | F2R (0.53) | F2RSMN1; SMN2USP2HSD17B10KDM4E | |
| SCHEMBL12720548 | 0.84 | F2R (0.53) | F2RRAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12720088 | 0.82 | F2R (0.54) | F2RRAB9ANPC1SMN1; SMN2GRM5 | |
| SCHEMBL12720294 | 0.81 | F2R (0.53) | F2RRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12720568 | 0.81 | GRM5 (0.47) | F2RRAB9ANPC1SMN1; SMN2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |