SCHEMBL127233

SCHEMBL127233

CCCCCCCCCCCCCCCCCC[SiH](C(C)C)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.44
SPHK1 Q9NYA1 1/20 0.39
DNM1 Q05193 6/20 0.38
OPRM1 P35372 1/20 0.36
TRPM8 Q7Z2W7 4/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475809 1.00 TSHR (0.44) TSHRTHRBSPHK1DNM1OPRM1
SCHEMBL449243 1.00 TSHR (0.44) TSHRTHRBSPHK1DNM1OPRM1
Fluoride SCHEMBL27854332 0.97 TSHR (0.42) TSHRTHRBSPHK1DNM1OPRM1
SCHEMBL2729272 0.97 TSHR (0.39) TSHRTHRBSPHK1DNM1OPRM1
SCHEMBL475837 0.88 TSHR (0.35) TSHRTHRBSPHK1OPRM1LMNA
SCHEMBL15914828 0.79 TSHR (0.40) TSHRTHRBSPHK1DNM1OPRM1
SCHEMBL1557239 0.78 TSHR (0.44) TSHRTHRBDNM1OPRM1TRPM8
SCHEMBL15916644 0.78 TSHR (0.44) TSHRTHRBDNM1OPRM1TRPM8
Decane SCHEMBL28143340 0.71 TSHR (0.73) TSHRTHRBDNM1OPRM1ALDH1A1
Isobutane SCHEMBL28169778 0.71 TSHR (0.73) TSHRTHRBDNM1OPRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
EP-1208167-B1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES HEMPELS SKIBSFARVE FAB J C (DK) 2003-07-30 EP claimed
CN-118159603-A Resin composition, method for producing resin composition, molding material, and article 三菱化学株式会社 2024-06-07 CN disclosed
WO-2024101418-A1 RESIN COMPOSITION AND MOLDED BODY MCPPイノベーション合同会社 2024-05-16 WO disclosed
US-11884813-B2 Macromonomer copolymer, epoxy resin composition, adhesive, molding material, and cured product MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-30 US disclosed
US-11767446-B2 (Meth)acrylic copolymer, coating material composition, coated article and method for forming multilayer coating film MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-26 US disclosed
US-11732144-B2 Polymer-containing composition and antifouling coating composition MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-22 US disclosed
US-11643489-B2 (Meth)acrylic copolymer, polymer solution, polymer-containing composition, anti-fouling coating composition, and method for producing (meth)acrylic copolymer MITSUBISHI CHEMICAL CORPORATION (JP) 2023-05-09 US disclosed
US-5767171-A A MARINE, HYDROLYZABLE, ANTIFOULING, PROTECTIVE COATING BASED ON A POLYMER OF A TRIALKYLSILYL (METH)ACRYLATE AND AN ALKYLOXYALKYL (METH)ACRYLATE; NONCRACKING; UNIFORM EROSION; ADHESION NOF CORPORATION (JP) 1998-06-16 US disclosed
EP-0714957-B1 Hydrolyzable self-polishing coating composition NOF CORP (JP) 1998-03-04 EP disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed
EP-0646630-B1 Antifouling coating composition NOF CORP (JP) 1997-04-23 EP disclosed
EP-0714957-A1 Hydrolyzable self-polishing coating composition NOF CORPORATION (JP) 1996-06-05 EP disclosed
US-5436284-A Preventing attachment of organisms to surfaces of structures submerged in seawater NOF CORPORATION (JP) 1995-07-25 US disclosed
EP-0646630-A1 Antifouling coating composition NOF CORPORATION (JP) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 TSHR 3690/4885THRB 4122/4885SPHK1 2300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.