SCHEMBL475837

SCHEMBL475837

CCCC[SiH](C(C)C)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
LMNA P02545 1/20 0.35
OPRM1 P35372 1/20 0.33
THRB P10828 1/20 0.33
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2729272 0.91 TSHR (0.39) TSHRLMNAOPRM1THRBSPHK1
SCHEMBL127233 0.88 TSHR (0.44) TSHRLMNAOPRM1THRBSPHK1
SCHEMBL475809 0.88 TSHR (0.44) TSHRLMNAOPRM1THRBSPHK1
SCHEMBL449243 0.88 TSHR (0.44) TSHRLMNAOPRM1THRBSPHK1
Fluoride SCHEMBL27854332 0.86 TSHR (0.42) TSHRLMNAOPRM1THRBSPHK1
SCHEMBL1325612 0.80
SCHEMBL9421591 0.77 TSHR (0.32) TSHRLMNAOPRM1THRBSPHK1
SCHEMBL15915163 0.77 TSHR (0.32) TSHRLMNAOPRM1THRBSPHK1
SCHEMBL704435 0.75
SCHEMBL4386834 0.75 TSHR (0.35) TSHRLMNAOPRM1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
EP-1476509-B1 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2007-04-11 EP claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP claimed
EP-1476509-A2 SELF-POLISHING ANTIFOULING PAINT Jotun AS (NO) 2004-11-17 EP claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO claimed
WO-2003070832-A2 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2003-08-28 WO claimed
EP-1208167-B1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES HEMPELS SKIBSFARVE FAB J C (DK) 2003-07-30 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
CN-113906036-B Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-10-25 CN disclosed
CN-111936505-B Tertiary alkyl-substituted polycyclic aromatic compounds and uses thereof 学校法人关西学院 2024-07-02 CN disclosed
EP-0714957-A1 Hydrolyzable self-polishing coating composition NOF CORPORATION (JP) 1996-06-05 EP disclosed
US-5436284-A Preventing attachment of organisms to surfaces of structures submerged in seawater NOF CORPORATION (JP) 1995-07-25 US disclosed
EP-0646630-A1 Antifouling coating composition NOF CORPORATION (JP) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 TSHR 2005/4885LMNA 2542/4885OPRM1 872/4885
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 TSHR 3690/4885LMNA 3271/4885OPRM1 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.