D-Glutamate

D-Glutamate

SCHEMBL127235

N[C@H](CCC(=O)O)C(=O)O.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.95
GRM6 O15303 2/20 0.95
GRM7 Q14831 2/20 0.95
GRM4 Q14833 2/20 0.95
GSR P00390 2/20 0.95
GRIN2D O15399 1/20 0.95
GRIN3B O60391 1/20 0.95
CYP1A2 P05177 1/20 0.95
GRIK1 P39086 1/20 0.95
GRM5 P41594 1/20 0.95
GRIA1 P42261 1/20 0.95
GRIA2 P42262 1/20 0.95
GRIA3 P42263 1/20 0.95
SLC1A3 P43003 1/20 0.95
SLC1A2 P43004 1/20 0.95
SLC1A1 P43005 1/20 0.95
GRIA4 P48058 1/20 0.95
GRIN1 Q05586 1/20 0.95
GRIN2A Q12879 1/20 0.95
GRIK2 Q13002 1/20 0.95

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL382517 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL17944 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL170872 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL26086434 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL330962 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL4605044 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL25423978 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1269250 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL333301 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL26086436 1.00 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3879 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081135-A Lactobacillus plantarum strain enriched in gamma-aminobutyric acid and application 2026-05-26 CN claimed
EP-4743192-A2 ENHANCED UTILISATION OF MICROALGAE BIOMASS AND EDIBLE FILM-FORMING COMPOSITIONS Marea ehf. (IS) 2026-05-20 EP claimed
CN-122060028-A Litopenaeus vannamei head delicious peptide and preparation method thereof 中国海洋大学三亚海洋研究院 2026-05-19 CN claimed
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
CN-122030599-A Chinese salty fresh full-nutrition special medical food based on flavor-physiological metabolism coupling mechanism 陈文洁 2026-05-15 CN claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
US-20250354183-A1 METHOD FOR PRODUCING L-GLUTAMIC ACID AJINOMOTO CO., INC. (JP) 2025-11-20 US claimed
US-20250346934-A1 SELF-ASSEMBLY ENZYME SYSTEM SUPPLYING A-KETOGLUTARATE AND APPLICATION THEREOF IN CATALYTIC SYNTHESIS OF 4-HYDROXYISOLEUCINE UNIV JIANGNAN (CN) 2025-11-13 US claimed
CN-120189444-A A probiotic preparation containing salt of dyers woad for improving gastrointestinal environment and its preparation method 内蒙古蒙盐科技有限责任公司 2025-06-24 CN claimed
CN-120131453-A W/O/W type emulsified composition 株式会社资生堂 2025-06-13 CN claimed
EP-0081236-B1 A COMPOUND SEASONING COMPOSITION, A PROCESS FOR ITS PRODUCTION AND ITS USE AS A FOOD COMPONENT AJINOMOTO CO., INC. (JP) 1986-04-23 EP claimed
US-4563359-A MIXTURE OF GLUTAMIC ACID WITH SODIUM AND POTASSIUM SALTS AJINOMOTO COMPANY, LIMITED (JP) 1986-01-07 US claimed
EP-0060903-B1 A DIPEPTIDE SWEETENING COMPOSITION AND ITS USE FOR SWEETENING FOOD, BEVERAGES OR PHARMACEUTICAL COMPOSITIONS AJINOMOTO CO., INC. (JP) 1984-12-05 EP claimed
EP-0125021-A1 Seasoning composition Takeda Chemical Industries, Ltd. (JP) 1984-11-14 EP claimed
EP-0031162-B1 MIXED SEASONING ON BASIS OF MONOSODIUM L-GLUTAMATE AJINOMOTO CO., INC. (JP) 1983-10-12 EP claimed
EP-0090673-A2 Image-forming elements KONICA CORPORATION (JP) 1983-10-05 EP claimed
US-4399162-A METHYL OR ETHYL ESTER OF ASPARTYLPHENYLALANINE, FLAVORS, MONOSODIUM GLUTAMATE AJINOMOTO COMPANY, INC. (JP) 1983-08-16 US claimed
EP-0081236-A1 A compound seasoning composition, a process for its production and its use as a food component AJINOMOTO CO., INC. (JP) 1983-06-15 EP claimed
EP-0060903-A1 A dipeptide sweetening composition and its use for sweetening food, beverages or pharmaceutical compositions AJINOMOTO CO., INC. (JP) 1982-09-29 EP claimed
US-4035513-A COSMETICS SHISEIDO CO., LTD. (JA) 1977-07-12 US claimed