Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.95 |
| ▸ | GRM6 | O15303 | 2/20 | 0.95 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.95 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.95 |
| ▸ | GSR | P00390 | 2/20 | 0.95 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.95 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.95 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.95 |
| ▸ | GRM5 | P41594 | 1/20 | 0.95 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.95 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.95 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.95 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.95 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.95 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.95 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.95 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.95 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.95 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL382517 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL17944 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL170872 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL26086434 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL330962 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL4605044 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL25423978 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL1269250 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL26086436 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL127235 | 1.00 | GRM8 (0.95) | GRM8GRM6GRM7GRM4GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153763-B2 | Heteromeric T1R2/T1R3 taste receptors | SENOMYX, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-8119402-B2 | Methods of inhibiting T1R1/T1R3 heteromeric umami taste receptors | SENOMYX, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20120015410-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2012-01-19 | — | — | US | disclosed |
| US-8097426-B2 | Methods of screening T1R2/T1R3 receptors for compounds which modulate sweet taste signaling | SENOMYX, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-8067185-B2 | Methods of quantifying taste of compounds for food or beverages | SENOMYX, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110262937-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS AND CELL LINES THAT EXPRESS SAID RECEPTORS AND USE THEREOF FOR IDENTIFICATION OF TASTE COMPOUNDS | SENOMYX, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-8039590-B2 | comprises polypeptide comprised of extracellular and transmembrane domains; modulate sweet or umami taste; g-protein coupled receptors | SENOMYX, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-8030052-B2 | Midecamycin hyper producing strain | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20110207148-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS AND CELL LINES THAT EXPRESS SAID RECEPTORS AND USE THEREOF FOR IDENTIFICATION OF TASTE COMPOUNDS | SENOMYX, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110201028-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS AND CELL LINES THAT EXPRESS SAID RECEPTORS AND USE THEREOF FOR IDENTIFICATION OF TASTE COMPOUNDS | SENOMYX, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201020-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS AND CELL LINES THAT EXPRESS SAID RECEPTORS AND USE THEREOF FOR IDENTIFICATION OF TASTE COMPOUNDS | SENOMYX, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| EP-2327985-A2 | T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds | Senomyx, Inc. (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2319923-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | Meiji Seika Kaisha, Ltd. (JP) | 2011-05-11 | — | — | EP | disclosed |
| US-7927825-B2 | Methods of using T1R2/T1R3 heteromeric receptors to quantify taste of compounds for food or beverages | SENOMYX, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-7927651-B2 | Biosensor having nano wire for detecting food additive mono sodium glutamate and manufacturing method thereof | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-04-19 | — | — | US | disclosed |
| US-7910322-B2 | Methods for identifying compounds that modulate T1R1/T1R3 umami taste receptors | SENOMYX, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-7906328-B2 | Cell lines that express hetero oligomeric taste receptors | SENOMYX, INC. (US) | 2011-03-15 | — | — | US | disclosed |
| EP-2293067-A2 | T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds | Senomyx, Inc. (US) | 2011-03-09 | — | — | EP | disclosed |
| US-7888470-B2 | Chimeric T1R taste receptor polypeptides and nucleic acid sequences encoding and cell lines that express said chimeric T1R polypeptides | SENOMYX, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| EP-2008098-B1 | BIOSENSOR HAVING NANO WIRE FOR DETECTING FOOD ADDITIVE MONO SODIUM GLUTAMATE AND MANUFACTURING METHOD THEREOF | SEOUL NAT UNIV IND FOUNDATION (KR) | 2011-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015410-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | PNKP, COASY, FDPS | GRM8 3612/4885GRM6 3362/4885GRM7 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.