SCHEMBL127246

SCHEMBL127246

C[N]S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.57
PRSS1 P07477 2/20 0.57
PRSS2 P07478 2/20 0.57
PRSS3 P35030 2/20 0.57
GAA P10253 3/20 0.56
CYP2C19 P33261 2/20 0.53
HTT P42858 1/20 0.53
LMNA P02545 1/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA12 O43570 1/20 0.52
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
TLR9 Q9NR96 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
ALDH1A1 P00352 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14382173 0.83 F2 (0.55) F2PRSS1PRSS2PRSS3GAA
SCHEMBL5138891 0.82 F2 (0.59) F2PRSS1PRSS2PRSS3GAA
SCHEMBL663730 0.80 CYP2C19 (0.59) F2PRSS1PRSS2PRSS3GAA
SCHEMBL9057442 0.80 F2 (0.63) F2PRSS1PRSS2PRSS3GAA
SCHEMBL7303158 0.78 F2 (0.55) F2PRSS1PRSS2PRSS3CA1
SCHEMBL6363790 0.78 ALDH1A1 (0.57) F2PRSS1PRSS2PRSS3CA1
SCHEMBL7777272 0.78 F2 (0.55) F2PRSS1PRSS2PRSS3GAA
SCHEMBL7301352 0.78 F2 (0.55) F2PRSS1PRSS2PRSS3GAA
SCHEMBL2412815 0.78 F2 (0.55) F2PRSS1PRSS2PRSS3GAA
SCHEMBL7770967 0.78 F2 (0.55) F2PRSS1PRSS2PRSS3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1144384-B1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARM INC (US) 2007-10-31 EP claimed
US-4120960-A DIURETICS, SALURESIS THE BOOTS COMPANY LIMITED (GB) 1978-10-17 US claimed
US-3980673-A INSECTICIDES, ACARICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US claimed
CN-115872822-A Catalyst for olefin polymerization and process for producing olefin polymer in the presence of the catalyst 三井化学株式会社 2023-03-31 CN disclosed
CN-108047568-B Molded article and propylene resin composition 三井化学株式会社 2020-06-09 CN disclosed
CN-110869337-A Catalyst for olefin polymerization and process for producing olefin polymer in the presence of the catalyst 三井化学株式会社 2020-03-06 CN disclosed
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
EP-1243598-B1 PROCESS FOR THE POLYMERIZATION OF OLEFINS MITSUI CHEMICALS INC (JP) 2015-08-12 EP disclosed
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
EP-1876189-B1 Use of a Modified Ethylene/alpha-olefin Copolymer as Resin Modifier MITSUI CHEMICALS INC (JP) 2012-03-07 EP disclosed
US-20100317813-A1 SUPPORTED CATALYST FOR THE PREPARATION OF (CO)MONOMERS OF ETHYLENICALLY UNSATURATED MONOMERS SAUDI BASIC INDUSTRIES CORPORATION (SA) 2010-12-16 US disclosed
US-5591762-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
EP-0502314-A1 Benzimidazol, medicaments containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1992-09-09 EP disclosed
EP-0413224-A1 Fungicidal agent containing 1,2-naphthoquinones BASF Aktiengesellschaft (DE) 1991-02-20 EP disclosed
US-4183955-A Troponyl-oxamic acid derivatives for treating allergic conditions Ayerst. McKenna & Harrison Limited (CA) 1980-01-15 US disclosed
US-4132436-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1979-01-02 US disclosed
US-4125625-A ANTIALLERGENS AYERST, MCKENNA & HARRISON LIMITED (CA) 1978-11-14 US disclosed
US-4120960-A DIURETICS, SALURESIS THE BOOTS COMPANY LIMITED (GB) 1978-10-17 US disclosed
US-4119777-A BY OXIDATION OF A THIOAMIDE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1978-10-10 US disclosed
US-4057556-A ANTIALLERGENS AYERST, MCKENNA & HARRISON LTD. (CA) 1977-11-08 US disclosed