Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 3/20 | 0.39 |
| ▸ | TOP1 | P11387 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12731969 | 0.85 | TOP1 (0.41) | TOP1NPC1CCR1CCR5CCR8 | |
| SCHEMBL12731968 | 0.83 | CCR1 (0.43) | TOP1NPC1CCR1CCR5CCR8 | |
| SCHEMBL17014572 | 0.82 | TOP1 (0.43) | TOP1NPC1CCR1CCR5CCR8 | |
| SCHEMBL17014577 | 0.81 | TOP1 (0.42) | TOP1NPC1CCR1CCR5CCR8 | |
| SCHEMBL12731970 | 0.79 | KDM4E (0.36) | TOP1NPC1CCR1CCR5CCR8 | |
| SCHEMBL12731971 | 0.79 | TOP1 (0.38) | TOP1CCR1CCR5CCR8LMNA | |
| SCHEMBL12731987 | 0.79 | TOP1 (0.38) | TOP1CCR1CCR5CCR8LMNA | |
| SCHEMBL2733743 | 0.79 | GRM5 (0.41) | TOP1NPC1CCR1CCR5CCR8 | |
| SCHEMBL12731998 | 0.78 | CCR1 (0.40) | TOP1CCR1CCR8LMNATP53 | |
| SCHEMBL12731995 | 0.78 | BRD4 (0.39) | TOP1CCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7931975-B2 | Electroluminescent device containing a flouranthene compound | GLOBAL OLED TECHNOLOGY LLC (US) | 2011-04-26 | — | — | US | disclosed |
| US-7931975-B2 | Electroluminescent device containing a flouranthene compound | GLOBAL OLED TECHNOLOGY LLC (US) | 2011-04-26 | — | — | US | disclosed |
| US-20100117519-A1 | ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND | GLOBAL OLED TECHNOLOGY LLC | 2010-05-13 | — | — | US | disclosed |
| US-20100117519-A1 | ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND | GLOBAL OLED TECHNOLOGY LLC | 2010-05-13 | — | — | US | disclosed |