Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381302 | 0.84 | NPC1 (0.62) | NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL14351707 | 0.84 | NPC1 (0.62) | NPC1MAPTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8894953 | 0.82 | NPC1 (0.60) | NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL12732010 | 0.82 | NPC1 (0.43) | NPC1MAPTRAB9ADHFRALDH1A1 | |
| SCHEMBL12731899 | 0.82 | NPC1 (0.74) | NPC1MAPTRAB9ADHFRALDH1A1 | |
| SCHEMBL1338846 | 0.78 | NPC1 (0.51) | NPC1MAPTRAB9A | |
| SCHEMBL4748369 | 0.77 | NPC1 (0.50) | NPC1MAPTRAB9A | |
| SCHEMBL4748372 | 0.77 | NPC1 (0.50) | NPC1MAPTRAB9A | |
| SCHEMBL4750633 | 0.77 | NPC1 (0.50) | NPC1MAPTRAB9A | |
| SCHEMBL7386839 | 0.76 | MAPT (0.47) | NPC1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098479-A1 | CONDENSATION REACTION BY METAL CATALYST | MASHIMA KAZUSHI | 2011-04-28 | — | — | US | disclosed |
| US-7888513-B2 | Condensation reaction by metal catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20090198070-A1 | Condensation Reaction by Metal Catalyst | OSAKA UNIVERSITY (JP) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098479-A1 | CONDENSATION REACTION BY METAL CATALYST | C9, CBR3, C1R | NPC1 3683/4885MAPT 4285/4885RAB9A 3188/4885 |
| US-20090198070-A1 | Condensation Reaction by Metal Catalyst | C9, CBR3, C1R | NPC1 3683/4885MAPT 4285/4885RAB9A 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.