SCHEMBL12733142

SCHEMBL12733142

CCCCc1ccc(Oc2cc(O)ccc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.58
ALOX15 P16050 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
XBP1 P17861 1/20 0.50
ALOX12 P18054 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
IGF1R P08069 2/20 0.49
ESR1 P03372 2/20 0.49
ADRA2A P08913 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
TACR2 P21452 2/20 0.49
SLC6A2 P23975 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1837233 0.82 LTA4H (0.67) ALOX15LMNAHSD17B10MEN1KMT2A
SCHEMBL24707034 0.81 F2 (0.65) F2ALOX15LMNAHSD17B10MEN1
SCHEMBL20621568 0.79 F2 (0.58) F2MEN1KMT2AESR1POLB
SCHEMBL2878661 0.79
SCHEMBL2711865 0.78 MEN1 (0.56) F2MEN1KMT2AESR1
SCHEMBL12952805 0.78 F2 (0.42) F2ALOX15IGF1R
SCHEMBL5712264 0.78 LTA4H (0.51) ALOX15LMNAHSD17B10IGF1RESR1
SCHEMBL1835169 0.77 ESR1 (0.75) ALOX15LMNAHSD17B10MEN1MAPT
SCHEMBL2876240 0.77 CNR2 (0.45) F2
SCHEMBL145761 0.76 LTA4H (0.52) LMNAHSD17B10ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
EP-1818725-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Hodogaya Chemical Co., Ltd. (JP) 2007-08-15 EP disclosed