SCHEMBL12733792

SCHEMBL12733792

C=CC(=O)OCOc1ccc(C(=O)Oc2ccc(F)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MEN1 O00255 2/20 0.42
ATM Q13315 1/20 0.42
THRB P10828 2/20 0.41
MAPT P10636 1/20 0.41
NR4A2 P43354 1/20 0.40
MAOB P27338 3/20 0.40
PARP10 Q53GL7 2/20 0.40
LSS P48449 2/20 0.39
HSD17B10 Q99714 1/20 0.37
PRSS1 P07477 1/20 0.37
ACR P10323 1/20 0.37
TTR P02766 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12742904 0.96 KMT2A (0.44) KMT2AMEN1ATMTHRBMAPT
SCHEMBL16449833 0.93 THRB (0.46) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL16449870 0.93 THRB (0.46) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL16449879 0.93 THRB (0.46) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL742922 0.93 THRB (0.46) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL11917937 0.93 THRB (0.46) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL16449835 0.93 THRB (0.46) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL12723906 0.92 THRB (0.45) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL17734099 0.92 THRB (0.45) KMT2ATHRBMAPTPARP10HSD17B10
SCHEMBL12733799 0.92 THRB (0.45) KMT2ATHRBMAPTPARP10HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919009-B2 Polymerizable compounds and polymerizable compositions ADEKA CORPORATION (JP) 2011-04-05 US disclosed
US-7910021-B2 Polymerizable optical active compound and polymerizable composition containing the same ADEKA CORPORATION (JP) 2011-03-22 US disclosed
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-7449223-B2 containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-11-11 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME C1S, PYM1, MCCC2 KMT2A 3291/4885MEN1 360/4885ATM 1048/4885
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS CHRM1, CHRM2, CCNE1 KMT2A 2784/4885MEN1 95/4885ATM 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.