SCHEMBL12735637

SCHEMBL12735637

CCCCc1ccc(-c2ccc(CCc3ccc(-c4ccc(CC)cc4)c(F)c3F)cc2)cc1F

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.41
RARA P10276 2/20 0.41
RARG P13631 1/20 0.41
MPL P40238 8/20 0.38
S1PR1 P21453 3/20 0.34
CHKA P35790 1/20 0.33
S1PR3 Q99500 2/20 0.33
TYR P14679 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12735631 0.94 RARB (0.41) RARBRARARARGMPLS1PR1
SCHEMBL10301992 0.93 RARB (0.40) RARBRARARARGMPLS1PR1
SCHEMBL12735619 0.93 RARB (0.37) RARBRARARARGMPLS1PR1
SCHEMBL12740078 0.91 MPL (0.40) RARBMPLCHKATYR
SCHEMBL12716997 0.91 MPL (0.40) RARBMPLCHKATYR
SCHEMBL12735630 0.90 RARB (0.46) RARBRARARARGMPLS1PR1
SCHEMBL12740126 0.90 RARB (0.41) RARBRARARARGMPLS1PR1
SCHEMBL12740162 0.89 RARB (0.43) RARBRARARARGMPLS1PR1
SCHEMBL10301938 0.89 RARB (0.48) RARBRARARARGMPLS1PR1
SCHEMBL10302000 0.88 RARB (0.40) RARBRARARARGMPLS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2011-04-21 US disclosed
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2011-04-21 US disclosed
WO-2009150966-A1 TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT チッソ株式会社 (JP) 2009-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, LAS1L, EFHD2 RARB 2705/4885RARA 2089/4885RARG 3220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.