Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 7/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.44 |
| ▸ | GCLC | P48506 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839696 | 0.85 | SLC1A1 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL3512082 | 0.83 | SLC7A5 (0.55) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL3510710 | 0.81 | SLC1A1 (0.47) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL7717181 | 0.80 | SLC1A1 (0.54) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL2994699 | 0.80 | SLC1A1 (0.54) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL6267781 | 0.80 | SLC1A1 (0.54) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL931954 | 0.80 | SLC1A1 (0.54) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL3430330 | 0.80 | SLC1A1 (0.54) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL3918242 | 0.80 | SLC1A1 (0.54) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL1410127 | 0.79 | SLC1A1 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112468-A1 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | Genentech, Inc. (US) | 2017-01-04 | — | — | EP | disclosed |
| US-20120128627-A1 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | CHEN JIAN (US) | 2012-05-24 | — | — | US | disclosed |
| US-8075888-B2 | Methods of treatment using antibodies to IL-17 homologous polypeptides | GENENTECH, INC. (US) | 2011-12-13 | — | — | US | disclosed |
| EP-2333069-A2 | Therapeutic uses of IL-17 homologous polypeptides | Genentech, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20110038868-A1 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | CHEN JIAN | 2011-02-17 | — | — | US | disclosed |
| EP-1076703-B2 | THERAPEUTIC USES OF IL-17 HOMOLOGOUS POLYPEPTIDES | GENENTECH INC (US) | 2010-12-15 | — | — | EP | disclosed |
| US-7749500-B2 | Antibodies to IL-17 polypeptides and therapeutic uses thereof | GENENTECH, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090022725-A1 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | CHEN JIAN | 2009-01-22 | — | — | US | disclosed |
| EP-1865061-A2 | IL-17 homologous polypeptides and therapeutic uses thereof | Genentech, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1076703-B1 | THERAPEUTIC USES OF IL-17 HOMOLOGOUS POLYPEPTIDES | GENENTECH INC (US) | 2007-06-27 | — | — | EP | disclosed |
| US-20070134238-A1 | Modulation of T Cell Differentiation for the Treatment of T Helper Cell Mediated Diseases | GENENTECH, INC. (US) | 2007-06-14 | — | — | US | disclosed |
| US-7217412-B2 | IL-17C related mammalian cytokine polypeptides | GENENTECH, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7115398-B2 | IL-17 homologous polypeptides and therapeutic uses thereof | GENENTCH, INC. (US) | 2006-10-03 | — | — | US | disclosed |
| US-20060205038-A1 | IL-I7 homologous polypeptides and therapeutic uses thereof | GENENTECH, INC | 2006-09-14 | — | — | US | disclosed |
| US-20020106743-A1 | IL-17 homologous polypeptides and therapeutic uses thereof | GENENTECH, INC. | 2002-08-08 | — | — | US | disclosed |
| US-20020052027-A1 | IL-17 homologous polypeptides and therapeutic uses thereof | GENENTECH, INC. | 2002-05-02 | — | — | US | disclosed |
| EP-1076703-A2 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | Genentech, Inc. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999060127-A9 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | GENENTECH INC (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999060127-A2 | IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF | GENENTECH, INC. (US) | 1999-11-25 | — | — | WO | disclosed |