SCHEMBL839696

SCHEMBL839696

CCC(N)C(=O)OC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC1A1 P43005 4/20 0.48
▸ SLC1A3 P43003 3/20 0.48
▸ SLC1A2 P43004 3/20 0.48
▸ GRIK1 P39086 3/20 0.48
▸ GRIK2 Q13002 2/20 0.48
▸ GSR P00390 2/20 0.48
▸ GRIA4 P48058 2/20 0.48
▸ GRIK3 Q13003 2/20 0.48
▸ GRIK5 Q16478 2/20 0.48
▸ GRM8 O00222 1/20 0.48
▸ GRM6 O15303 1/20 0.48
▸ GRIN2D O15399 1/20 0.48
▸ GRIN3B O60391 1/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ GRM5 P41594 1/20 0.48
▸ GRIA1 P42261 1/20 0.48
▸ GRIA2 P42262 1/20 0.48
▸ GRIA3 P42263 1/20 0.48
▸ GRIN1 Q05586 1/20 0.48
▸ GRIN2A Q12879 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267781 0.87 SLC1A1 (0.54) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL2994699 0.87 SLC1A1 (0.54) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL7717181 0.87 SLC1A1 (0.54) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL931954 0.87 SLC1A1 (0.54) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL3918242 0.87 SLC1A1 (0.54) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL3430330 0.87 SLC1A1 (0.54) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL1273617 0.85 SLC1A1 (0.50) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL5604914 0.85 SLC1A1 (0.52) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL9857204 0.85 SLC1A1 (0.52) SLC1A1SLC1A3SLC1A2GRIK1GRIK2
SCHEMBL27976398 0.85 SLC1A1 (0.52) SLC1A1SLC1A3SLC1A2GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH UNIV CALIFORNIA (US) 2026-03-19 — — US disclosed
US-20220102000-A1 PREDICTING BLOOD METABOLITES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-03-31 — — US disclosed
EP-3918603-A1 PREDICTING BLOOD METABOLITES Yeda Research and Development Co. Ltd (IL) 2021-12-08 — — EP disclosed
US-10634686-B2 Biomarkers related to organ function University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2020-04-28 — — US disclosed
US-10175233-B2 Biomarkers for cardiovascular diseases and methods using the same METABOLON, INC. (US) 2019-01-08 — — US disclosed
WO-2017029498-A1 2-SULFONYLPYRIMIDINES MEDICAL RESEARCH COUNCIL (GB) 2017-02-23 — — WO disclosed
US-20160231330-A1 BIOMARKERS RELATED TO ORGAN FUNCTION UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2016-08-11 — — US disclosed
US-20160178620-A1 Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and other Metabolic-Syndrome Related Disorders and Methods Using the Same METABOLON, INC. 2016-06-23 — — US disclosed
US-9250225-B2 Biomarkers for insulin resistance and methods using the same METABOLON, INC. (US) 2016-02-02 — — US disclosed
WO-2015042602-A1 BIOMARKERS RELATED TO ORGAN FUNCTION UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2015-03-26 — — WO disclosed
US-7405227-B2 Treatment of cancer BIPAR SCIENCES, INC. (US) 2008-07-29 — — US disclosed
US-20080103104-A1 TREATMENT OF CANCER BIPAR SCIENCES, INC. (US) 2008-05-01 — — US disclosed
EP-1906948-A2 TREATMENT OF CANCER Bipar Sciences, Inc. (US) 2008-04-09 — — EP disclosed
WO-2007011962-A2 TREATMENT OF CANCER BIPAR SCIENCES, INC. (US) 2007-01-25 — — WO disclosed
US-20070015837-A1 Treatment of Cancer BIPAR SCIENCES, INC. 2007-01-18 — — US disclosed
US-6127165-A NUCLEIC ACID WHICH ENCODES ENZYME HAVING DEFINED AMINO ACID SEQUENCE; USED TO PREPARE GLUTATHIONE ANALOGS AND ANTIBODIES AGAINST ENZYME, DETECT GENE IN ANIMALS, MODIFY ENZYME PRODUCTION, CONSTRUCT MODELS FOR EVALUATION OF THERAPIES CORNELL RESEARCH FOUNDATION, INC. (US) 2000-10-03 — — US disclosed
US-5747329-A Glutamylcysteine synthetase light subunit CORNELL RESEARCH FOUNDATION, INC. (US) 1998-05-05 — — US disclosed
EP-0693122-A4 GLUTAMYLCYSTEINE SYNTHETASE LIGHT SUBUNIT CORNELL RES FOUNDATION INC (US) 1997-10-22 — — EP disclosed
EP-0693122-A1 GLUTAMYLCYSTEINE SYNTHETASE LIGHT SUBUNIT CORNELL RESEARCH FOUNDATION, INC. (US) 1996-01-24 — — EP disclosed
WO-1994024276-A1 GLUTAMYLCYSTEINE SYNTHETASE LIGHT SUBUNIT CORNELL RESEARCH FOUNDATION, INC. (US) 1994-10-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015837-A1 Treatment of Cancer PARP1, PARP2, PARP3 SLC1A1 4710/4885SLC1A3 4794/4885SLC1A2 4845/4885
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH IDO1, INMT, IDO2 SLC1A1 149/4885SLC1A3 141/4885SLC1A2 94/4885
US-20080103104-A1 TREATMENT OF CANCER PARP1, PARP2, PARP3 SLC1A1 4710/4885SLC1A3 4794/4885SLC1A2 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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