Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779324 | 0.82 | TP53 (0.38) | TP53FAAHCA1CA2 | |
| SCHEMBL14837195 | 0.80 | TP53 (0.36) | TP53FAAHCA1CA2 | |
| SCHEMBL14836362 | 0.80 | TP53 (0.36) | TP53FAAHCA1CA2 | |
| SCHEMBL14779662 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL575691 | 0.78 | — | — | |
| SCHEMBL5277106 | 0.77 | CA12 (0.31) | CA1CA2 | |
| SCHEMBL14778709 | 0.76 | TP53 (0.45) | TP53FAAHCA1CA2 | |
| SCHEMBL8342378 | 0.76 | TP53 (0.39) | TP53FAAHCA1CA2 | |
| SCHEMBL14778634 | 0.75 | TP53 (0.44) | TP53FAAHCA1CA2 | |
| SCHEMBL14836535 | 0.75 | TP53 (0.44) | TP53FAAHCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150182672-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150182672-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-07-02 | — | — | US | disclosed |
| US-9067001-B2 | Coatings for implantable medical devices | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20140038907-A1 | Coatings For Implantable Medical Devices | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8563025-B2 | Coatings for implantable medical devices | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-7919075-B1 | Coatings for implantable medical devices | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-04-05 | — | — | US | disclosed |