Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.31 |
| ▸ | TSPO | P30536 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12741059 | 1.00 | MAPT (0.35) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12737642 | 0.91 | KDM1A (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2 | |
| SCHEMBL14922550 | 0.90 | MAPT (0.40) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12737597 | 0.89 | MAPT (0.35) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12741058 | 0.89 | MAPT (0.35) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12737685 | 0.88 | CPS1 (0.36) | CAMKK1CAMKK2ACACB | |
| SCHEMBL12737601 | 0.86 | MAPT (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL14767243 | 0.86 | MAPT (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12822542 | 0.86 | SMN1; SMN2 (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL15381579 | 0.86 | MAPT (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| US-20110090450-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110090450-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | LEF1, LAS1L, EFHD2 | MAPT 1075/4885SMN1; SMN2 3745/4885CAMKK1 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.