SCHEMBL1273993

SCHEMBL1273993

CCCC(=O)OCC=C(C)C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.44
TRPV1 Q8NER1 2/20 0.43
DGKA P23743 1/20 0.38
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP12 P39900 1/20 0.37
TTR P02766 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27611614 0.89 ALDH1A1 (0.50) ALDH1A1ALOX15TSHRTRPV1MMP1
SCHEMBL2418388 0.86 TSHR (0.62) ALDH1A1TSHRDGKA
SCHEMBL118466 0.85 ALDH1A1 (0.69) ALDH1A1ALOX15TRPV1
SCHEMBL118465 0.85 ALDH1A1 (0.69) ALDH1A1ALOX15TRPV1
SCHEMBL560282 0.85 ALDH1A1 (0.69) ALDH1A1ALOX15TRPV1
SCHEMBL1870463 0.85 ALDH1A1 (0.69) ALDH1A1ALOX15TRPV1
SCHEMBL901242 0.85 ALDH1A1 (0.69) ALDH1A1ALOX15TRPV1
SCHEMBL28579354 0.84 TSHR (0.66) ALDH1A1TSHRDGKA
SCHEMBL3503234 0.84 TSHR (0.66) ALDH1A1TSHRDGKA
SCHEMBL3505613 0.84 TSHR (0.66) ALDH1A1TSHRDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200298-B2 Host cells and methods for producing isoprenyl alkanoates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-12-01 US claimed
US-20100180491-A1 Host Cells and Methods for Producing Isoprenyl Alkanoates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-22 US claimed
WO-2009006386-A2 HOST CELLS AND METHODS FOR PRODUCING ISOPRENYL ALKANOATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-01-08 WO claimed
EP-2341042-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2019-03-20 EP disclosed
EP-2443163-B1 POLYMERIZATION OF ISOPRENE FROM RENEWABLE RESOURCES DANISCO US INC (US) 2018-12-26 EP disclosed
EP-3323881-A1 SYSTEMS USING CELL CULTURE FOR PRODUCTION OF ISOPRENE Danisco US Inc. (US) 2018-05-23 EP disclosed
EP-2344629-B1 SYSTEMS USING CELL CULTURE FOR PRODUCTION OF ISOPRENE DANISCO US INC (US) 2018-01-24 EP disclosed
US-9200298-B2 Host cells and methods for producing isoprenyl alkanoates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-12-01 US disclosed
US-8901262-B2 Polymerization of isoprene from renewable resources THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-12-02 US disclosed
US-8680328-B2 Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-25 US disclosed
US-20140080983-A1 POLYMERIZATION OF ISOPRENE FROM RENEWABLE RESOURCES DANISCO US INC. (US) 2014-03-20 US disclosed
EP-2341042-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-07-06 EP disclosed
US-7928253-B2 Method of producing 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-19 US disclosed
US-20110040058-A1 POLYMERIZATION OF ISOPRENE FROM RENEWABLE RESOURCES THE GOODYEAR TIRE & RUBBER COMPANY 2011-02-17 US disclosed
US-20100180491-A1 Host Cells and Methods for Producing Isoprenyl Alkanoates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-22 US disclosed
US-20100168463-A1 METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-01 US disclosed
US-20100167371-A1 SYSTEMS USING CELL CULTURE FOR PRODUCTION OF ISOPRENE THE GOODYEAR TIRE & RUBBER COMPANY 2010-07-01 US disclosed
WO-2009006386-A2 HOST CELLS AND METHODS FOR PRODUCING ISOPRENYL ALKANOATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-01-08 WO disclosed
EP-1950208-A1 PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE Sumitomo Chemical Company, Limited (JP) 2008-07-30 EP disclosed
US-4044041-A CARBOXYLIC ACID WITH CONJUGATED DIENE PHILLIPS PETROLEUM COMPANY (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168463-A1 METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE CYP1B1, HACL2, CMA1 ALDH1A1 147/4885ALOX15 650/4885TSHR 2332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.