Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | UBE2I | P63279 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541151 | 1.00 | CYP1A2 (0.41) | CYP1A2CYP2A6TRPM4ALDH1A1HSD17B10 | |
| SCHEMBL18055166 | 0.97 | CYP1A2 (0.39) | CYP1A2CYP2A6TRPM4ALDH1A1HSD17B10 | |
| SCHEMBL6282147 | 0.96 | CYP1A2 (0.41) | CYP1A2CYP2A6TRPM4ALDH1A1HSD17B10 | |
| SCHEMBL12744253 | 0.95 | GPR84 (0.40) | CYP1A2CYP2A6TRPM4ALDH1A1HSD17B10 | |
| SCHEMBL12744257 | 0.95 | CYP1A2 (0.38) | CYP1A2CYP2A6TRPM4ALDH1A1HSD17B10 | |
| SCHEMBL23790764 | 0.94 | HTT (0.42) | CYP1A2CYP2A6TRPM4ALDH1A1HSD17B10 | |
| SCHEMBL19735354 | 0.92 | GPR84 (0.41) | CYP1A2CYP2A6ALDH1A1HPGDTDP1 | |
| SCHEMBL23128255 | 0.92 | GPR84 (0.41) | CYP1A2CYP2A6ALDH1A1CYP1B1HPGD | |
| SCHEMBL22807963 | 0.92 | GPR84 (0.41) | CYP1A2CYP2A6ALDH1A1CYP1B1HPGD | |
| SCHEMBL21919221 | 0.92 | GPR84 (0.41) | CYP1A2CYP2A6ALDH1A1CYP1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910687-B2 | Conjugated polymers containing arylamine units, the representation thereof and the use of the same | MERCK PATENT GMBH (DE) | 2011-03-22 | — | — | US | disclosed |
| US-7910687-B2 | Conjugated polymers containing arylamine units, the representation thereof and the use of the same | MERCK PATENT GMBH (DE) | 2011-03-22 | — | — | US | disclosed |