Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000628 | 0.95 | GAA (0.39) | GAAPKMHTTHMGCRXBP1 | |
| SCHEMBL10064556 | 0.87 | KMT2A (0.39) | GAAPKMHTTHMGCRXBP1 | |
| SCHEMBL25141789 | 0.85 | HMGCR (0.39) | GAAPKMHTTHMGCRXBP1 | |
| SCHEMBL13492046 | 0.84 | HMGCR (0.39) | GAAPKMHTTHMGCRXBP1 | |
| SCHEMBL12919723 | 0.84 | ESR1 (0.35) | GAAPPARGLMNAPTGESALOX5 | |
| SCHEMBL19103209 | 0.83 | GAA (0.33) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL18027948 | 0.82 | PPARG (0.32) | PPARGPTGESALOX5 | |
| SCHEMBL7759198 | 0.81 | GAA (0.37) | GAAPKMHTTHMGCRXBP1 | |
| SCHEMBL13688317 | 0.81 | HMGCR (0.36) | GAAPKMHTTHMGCRXBP1 | |
| SCHEMBL3450269 | 0.81 | GAA (0.37) | GAAPKMHTTHMGCRXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910642-B2 | Stabilization of polyether polyol, polyester polyol or polyurethane compositions | BASF SE (DE) | 2011-03-22 | — | — | US | disclosed |