SCHEMBL10000628

SCHEMBL10000628

CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)OC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
HMGCR P04035 2/20 0.38
XBP1 P17861 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
PPARG P37231 2/20 0.35
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 2/20 0.34
KCNH2 Q12809 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12744431 0.95 GAA (0.36) GAAPKMHTTHMGCRXBP1
SCHEMBL10064556 0.91 KMT2A (0.39) GAAPKMHTTHMGCRXBP1
SCHEMBL25141789 0.89 HMGCR (0.39) GAAPKMHTTHMGCRXBP1
SCHEMBL12919723 0.89 ESR1 (0.35) GAAPPARGLMNAPTGESALOX5
SCHEMBL13492046 0.89 HMGCR (0.39) GAAPKMHTTHMGCRXBP1
SCHEMBL19103209 0.87 GAA (0.33) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL18027948 0.86 PPARG (0.32) PPARGPTGESALOX5
SCHEMBL3450269 0.85 GAA (0.37) GAAPKMHTTHMGCRXBP1
SCHEMBL7759198 0.85 GAA (0.37) GAAPKMHTTHMGCRXBP1
SCHEMBL13688317 0.85 HMGCR (0.36) GAAPKMHTTHMGCRXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026124-A1 USE OF DIEUGENOL, OLIGOMERS AND/OR POLYMERS OF EUGENOL FOR STABILIZING ORGANIC MATERIALS, STABILIZED PLASTICS COMPOSITION, STABILIZER COMPOSITION AND METHOD FOR STABILIZING ORGANIC MATERIALS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-25 US disclosed
US-11760865-B2 Halogen-free sulphonic acid ester and/or sulphinic acid ester as flame retardant, flame retardant synergists and radical generators in plastics Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-09-19 US disclosed
US-11760865-B2 Halogen-free sulphonic acid ester and/or sulphinic acid ester as flame retardant, flame retardant synergists and radical generators in plastics Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-09-19 US disclosed
US-11634560-B2 Efficient phosphorous stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-04-25 US disclosed
US-20230119120-A1 USE OF HYDROXYCINNAMIC ACID SALTS FOR STABILIZING ORGANIC MATERIALS, STABILIZED ORGANIC MATERIAL, METHOD FOR STABILIZING ORGANIC MATERIALS, SPECIFIC STABILIZERS AND STABILIZER COMPOSITIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-04-20 US disclosed
US-11591450-B2 Method for stabilizing halogen-free thermoplastic recyclates, stabilized plastic compositions, and molding compounds and molded parts produced therefrom Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-02-28 US disclosed
US-20220119624-A1 METHOD OF STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, PLASTICS COMPOSITION, STABILIZER COMPOSITION AND USE OF THE STABILIZER COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2022-04-21 US disclosed
US-20210388176-A1 METHOD OF STABILIZING VIRGIN THERMOPLASTIC MATERIAL AND STABILIZED PLASTICS COMPOSITIONS, MOULDING COMPOUNDS AND MOULDINGS PRODUCED THEREFROM, STABILIZER COMPOSITIONS AND USES THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2021-12-16 US disclosed
US-11118090-B2 Stabilization of hot melt adhesives BASF SE (DE) 2021-09-14 US disclosed
US-20210130582-A1 EFFICIENT PHOSPHOROUS STABILISERS BASED ON DIPHENYLAMINE AND HETEROCYCLIC DIPHENYLAMINE DERIVATIVES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-05-06 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-20080033080-A1 Stabilization of Polyether Polyol, Polyester Polyol or Polyurethane Compositions BASF SE (DE) 2008-02-07 US disclosed
US-20080009550-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2008-01-10 US disclosed
US-20070294837-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2007-12-27 US disclosed
US-20070203269-A1 COMPOSITIONS COMPRISING POLYPHOSPHONATES AND ADDITIVES THAT EXHIBIT AN ADVANTAGEOUS COMBINATION OF PROPERTIES, AND METHODS RELATED THERETO FRX POLYMERS, INC. 2007-08-30 US disclosed
US-20070151143-A1 Stabilized biodiesel fuel compositions CIBA SPECIALTY CHEMICALS CORP. 2007-07-05 US disclosed
US-20070135537-A1 Agricultural articles BONORA MICHAEL 2007-06-14 US disclosed
US-7205379-B2 reacting diacids or diesters with a diol in the presence of a stabilizer of a polyhydric alcohol, a phosphinic acid, a sterically hindered amine or a polyacrylamide; packaging with low aldehyde generation CIBA SPECIALTY CHEMICALS CORP. (US) 2007-04-17 US disclosed
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. 2007-04-12 US disclosed
US-7179924-B2 Use of benzotriazole UV absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CUTA, NISCH, DSC1 GAA 2601/4885PKM 3339/4885HTT 419/4885
US-11634560-B2 Efficient phosphorous stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives PNN, PNMT, PPA1 GAA 883/4885PKM 146/4885HTT 380/4885
US-20210130582-A1 EFFICIENT PHOSPHOROUS STABILISERS BASED ON DIPHENYLAMINE AND HETEROCYCLIC DIPHENYLAMINE DERIVATIVES PNMT, PNN, PPA1 GAA 752/4885PKM 124/4885HTT 240/4885
US-20070203269-A1 COMPOSITIONS COMPRISING POLYPHOSPHONATES AND ADDITIVES THAT EXHIBIT AN ADVANTAGEOUS COMBINATION OF PROPERTIES, AND METHODS RELATED THERETO PGM2, PICALM, PIK3CA GAA 1568/4885PKM 266/4885HTT 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.