SCHEMBL1274840

SCHEMBL1274840

CC(=O)OCCSCc1cc(C)c(O)c(CSCCOC(C)=O)c1C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.32
TNKS2 Q9H2K2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27510698 0.80 RAD52 (0.34) TNKS2ALDH1A1MEN1KMT2A
SCHEMBL10692792 0.76 TNKS2 (0.38) TNKS2ALDH1A1
SCHEMBL9576130 0.73 TYR (0.39) ESR1
SCHEMBL6699498 0.73 TYR (0.39) ESR1
SCHEMBL1275800 0.68 HSPA5 (0.41) TNKS2ALDH1A1MEN1KMT2A
SCHEMBL1274583 0.68
SCHEMBL11652510 0.66 ALDH1A1 (0.50) ALDH1A1
SCHEMBL31518753 0.64 CYP2C19 (0.56) ALDH1A1KMT2A
SCHEMBL25328523 0.63 ESR1 (0.40) ESR1ALDH1A1MEN1KMT2A
SCHEMBL31092527 0.63 ESR1 (0.40) ESR1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190233546-A1 Conjugated Diene-Based Polymer, Method for Producing the Same, and Composition Including the Same JAPAN ELASTOMER CO., LTD. (JP) 2019-08-01 US disclosed
US-10316111-B2 Conjugated diene-based polymer, method for producing the same, and composition including the same ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-06-11 US disclosed
EP-3150638-B1 CONJUGATED DIENE POLYMER, METHOD FOR PRODUCING SAME, AND COMPOSITION INCLUDING SAME JAPAN ELASTOMER CO LTD (JP) 2018-11-07 EP disclosed
US-20170190805-A1 Conjugated Diene-Based Polymer, Method for Producing the Same, and Composition Including the Same JAPAN ELASTOMER CO., LTD. (JP) 2017-07-06 US disclosed
EP-3150638-A1 CONJUGATED DIENE POLYMER, METHOD FOR PRODUCING SAME, AND COMPOSITION INCLUDING SAME Japan Elastomer Co., Ltd. (JP) 2017-04-05 EP disclosed
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7534824-B2 Polymer composition and process for producing the same JSR CORPORATION (JP) 2009-05-19 US disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
US-6486258-B1 Conjugated diene rubber composition for tire use and tire ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
US-6448336-B1 AROMATIC VINYL MONOMER POLYMERIZED WITH CONJUGATED DIENE POLYMER RUBBER; LOW TEMPERATURE IMPACT RESISTANCE; LUSTER ZEON CORP. (JP) 2002-09-10 US disclosed
US-6342559-B1 COPOLYMERS WITH ACRYLIC ESTERS, ACRYLAMIDE DERIVATIVES, HYDROXYALKYL(METH)ACRYLATES WITH DIENE AND STYRENE TERPOLYMERS (METH)ACRYLATE MODIFIED WITH TERTIARY ALKYL THIOL; FRICTION RESISTANT TIRE TREADS ZEON CORPORATION (JP) 2002-01-29 US disclosed
EP-1148093-A1 CONJUGATED DIENE RUBBER COMPOSITION FOR TIRE USE AND TIRE Nippon Zeon Co., Ltd. (JP) 2001-10-24 EP disclosed
EP-1146059-A1 RESIN MODIFIER, RESIN COMPOSITION CONTAINING THE SAME, AND POLYAROMATIC VINYL RESIN COMPOSITION Nippon Zeon Co., Ltd. (JP) 2001-10-17 EP disclosed
EP-1081162-A1 CONJUGATED DIENE RUBBER, PROCESS FOR PRODUCING THE SAME, AND RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 2001-03-07 EP disclosed
EP-1054026-A1 BUTADIENE POLYMERS AND PROCESS FOR PRODUCING CONJUGATED DIENE POLYMERS JAPAN as Represented by DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2000-11-22 EP disclosed
EP-0224442-B1 USE OF SUBSTITUTED PHENOLS AS STABILIZERS CIBA-GEIGY AG (CH) 1990-05-16 EP disclosed
US-4857572-A ELASTOMERS AND TACKIFIER RESINS CIBA-GEIGY CORPORATION (US) 1989-08-15 US disclosed