⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18199914 | 0.67 | — | — | |
| SCHEMBL3626952 | 0.67 | — | — | |
| SCHEMBL14360974 | 0.67 | — | — | |
| SCHEMBL6243003 | 0.67 | — | — | |
| SCHEMBL1162653 | 0.67 | — | — | |
| SCHEMBL12569212 | 0.63 | — | — | |
| SCHEMBL16794757 | 0.62 | — | — | |
| SCHEMBL10766052 | 0.62 | — | — | |
| SCHEMBL11007419 | 0.62 | — | — | |
| SCHEMBL4022348 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172392-A1 | AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | SALTER-CID LUISA M (US) | 2012-07-05 | — | — | US | disclosed |
| EP-2283833-A2 | Amines and amides for the treatment of diseases | LA JOLLA PHARMACEUTICAL CO. (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20070078157-A1 | Amine-based and amide-based inhibitors of semicarbazide-sensitive amine oxidase (SSAO)enzyme activity and VAP-1 mediated adhesion useful for treatment of diseases | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-04-05 | — | — | US | disclosed |
| EP-1732531-A2 | AMINES AND AMIDES FOR THE TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2006-12-20 | — | — | EP | disclosed |
| US-20060025438-A1 | Amine-based and amide-based inhibitors of semicarbazide-sensitive amine oxidase (SSAO) enzyne activity and VAP-1 mediated adhesion useful for treatment of diseases | LA JOLLA PHARMACEUTICAL COMPANY | 2006-02-02 | — | — | US | disclosed |
| WO-2005082343-A2 | AMINES AND AMIDES FOR THE TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |