SCHEMBL12749541

SCHEMBL12749541

CCCCCCCCCCCCSSC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 2/20 0.47
DNM1 Q05193 8/20 0.43
HSD17B10 Q99714 2/20 0.39
CES2 O00748 1/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
BLM P54132 1/20 0.39
CA2 P00918 1/20 0.38
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945031 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL10941688 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL3380906 1.00
SCHEMBL3379274 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL11847801 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL10949053 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL31244850 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL31651405 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL3379235 0.97
SCHEMBL575853 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250219129-A1 SOLID-STATE ELECTROLYTE SYNTHESIS USING A SULFUR-CONTAINING ADDITIVE Solid Power Operating, Inc. 2025-07-03 US claimed
US-20250219129-A1 SOLID-STATE ELECTROLYTE SYNTHESIS USING A SULFUR-CONTAINING ADDITIVE Solid Power Operating, Inc. 2025-07-03 US disclosed
EP-2164992-B1 COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID LPATH INC (US) 2016-05-04 EP disclosed
US-20140199293-A1 HUMANIZED ANTIBODY COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID APOLLO ENDOSURGERY, INC. 2014-07-17 US disclosed
US-7915810-B2 Display device, and method for repairing a defective pixel FUJIFILM CORPORATION (JP) 2011-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140199293-A1 HUMANIZED ANTIBODY COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID LPAR5, LPAR2, LPAR6 TSHR 2239/4885THRB 2844/4885DNM1 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.