SCHEMBL3379274

SCHEMBL3379274

CCCCCCCSSC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 2/20 0.47
DNM1 Q05193 8/20 0.43
HSD17B10 Q99714 2/20 0.39
CES2 O00748 1/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
BLM P54132 1/20 0.39
CA2 P00918 1/20 0.38
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945031 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL10941688 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL3380906 1.00
SCHEMBL12749541 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL11847801 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL10949053 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL31244850 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL31651405 1.00 TSHR (0.47) TSHRTHRBDNM1HSD17B10CES2
SCHEMBL3379235 0.97
SCHEMBL575853 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250219129-A1 SOLID-STATE ELECTROLYTE SYNTHESIS USING A SULFUR-CONTAINING ADDITIVE Solid Power Operating, Inc. 2025-07-03 US claimed
US-20250219129-A1 SOLID-STATE ELECTROLYTE SYNTHESIS USING A SULFUR-CONTAINING ADDITIVE Solid Power Operating, Inc. 2025-07-03 US disclosed
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2020-10-20 US disclosed
EP-2659275-B1 DETECTION OF A POLYPEPTIDE DIMER BY A BIVALENT BINDING AGENT ROCHE DIAGNOSTICS GMBH (DE) 2017-11-22 EP disclosed
US-20170114341-A1 POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS BRADSHAW CURT W (US) 2017-04-27 US disclosed
WO-2015188197-A2 POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS SOLSTICE BIOLOGICS, LTD. (IE) 2015-12-10 WO disclosed
WO-2015069932-A1 POLYNUCLEOTIDE CONSTRUCTS HAVING DISULFIDE GROUPS SOLSTICE BIOLOGICS, LTD. (IE) 2015-05-14 WO disclosed
US-8470855-B2 Dual-use peptidase inhibitors as prodrugs for a therapy of inflammatory and other diseases IMTM GMBH (DE) 2013-06-25 US disclosed
US-20130109817-A1 Modified Polymers for Delivery of Polynucleotides, Method of Manufacture, and Methods of Use Thereof MERSANA THERAPEUTICS, INC. (US) 2013-05-02 US disclosed
US-8349308-B2 Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof MERSANA THERAPEUTICS, INC. (US) 2013-01-08 US disclosed
CN-101253256-B Method for desulfurization of hydrocarbon oil JAPAN ENERGY CORP 2011-11-16 CN disclosed
US-20110243880-A1 MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF MERSANA THERAPEUTICS, INC. (US) 2011-10-06 US disclosed
US-20100155303-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2010-06-24 US disclosed
CN-101253256-A Method for desulfurization of hydrocarbon oil JAPAN ENERGY CORP (JP) 2008-08-27 CN disclosed
EP-1923451-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2008-05-21 EP disclosed
US-4544796-A Solvent extraction of aromatic compounds using alkylsulfoxide solvents UOP INC. (US) 1985-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation RTCB, IGF2BP2, SNRPE TSHR 271/4885THRB 552/4885DNM1 1874/4885
US-20110243880-A1 MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF ZYX, NSUN3, NSUN2 TSHR 1793/4885THRB 3040/4885DNM1 1400/4885
US-20170114341-A1 POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS HNRNPC, RNASE1, NSUN3 TSHR 3447/4885THRB 4169/4885DNM1 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.