SCHEMBL127567

SCHEMBL127567

OCc1ccc(Br)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30509941 1.00
SCHEMBL5628 0.82 CYP11B1 (0.43)
SCHEMBL1134968 0.79 CYP11B1 (0.41)
SCHEMBL29725206 0.78
SCHEMBL485115 0.78
SCHEMBL1874065 0.77 CA2 (0.41)
SCHEMBL1274691 0.76
SCHEMBL2180629 0.76
SCHEMBL1193384 0.76
SCHEMBL507586 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301403-B1 CURING AGENT FOR SYNTHETIC RESINS, COMPOSITIONS CONTAINING THE SAME AND USES OF THEM HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-15 EP claimed
US-4847346-A HYDROXYALKYLPYRIDINE BLOCKED DIISOCYANATES AS CURING AGENTS HOECHST AG (DE) 1989-07-11 US claimed
EP-0301403-A2 Curing agent for synthetic resins, compositions containing the same and uses of them HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP claimed
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF KARYOPHARM THERAPEUTICS INC (US) 2026-03-26 US disclosed
US-12552772-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD SPRINGWORKS THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
EP-4688772-A1 BIARYL DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-02-11 EP disclosed
US-12534453-B2 Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof MAZE THERAPEUTICS, INC. (US) 2026-01-27 US disclosed
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 US disclosed
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2026-01-15 US disclosed
US-20250325552-A1 SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES INC (US) 2025-10-23 US disclosed
US-20250257049-A1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF MGLUR7 PRAGMA THERAPEUTICS (FR) 2025-08-14 US disclosed
US-5256654-A Substituted pyrrolopyrimidines, azepinopyrimidines and pyridopyrimidines useful as angiotensin II antagonists AMERICAN HOME PRODUCTS CORPORATION (US) 1993-10-26 US disclosed
US-5219868-A Insecticides MITSUI TOATSU CHEMICALS, INC. (JP) 1993-06-15 US disclosed
CN-1072682-A SUBSTITUTED PYRIMIDINES AMERICAN HOME PROD (US) 1993-06-02 CN disclosed
EP-0539086-A2 Condensed pyrimidine derivatives and their use as angiotensine II antagonists AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-28 EP disclosed
US-5149699-A Substituted pyridopyrimidines useful as antgiotensin II antagonists AMERICAN HOME PRODUCTS CORPORATION (US) 1992-09-22 US disclosed
EP-0301403-B1 CURING AGENT FOR SYNTHETIC RESINS, COMPOSITIONS CONTAINING THE SAME AND USES OF THEM HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-15 EP disclosed
EP-0490323-A1 Imidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-06-17 EP disclosed
US-4847346-A HYDROXYALKYLPYRIDINE BLOCKED DIISOCYANATES AS CURING AGENTS HOECHST AG (DE) 1989-07-11 US disclosed
EP-0301403-A2 Curing agent for synthetic resins, compositions containing the same and uses of them HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP disclosed