SCHEMBL127573

SCHEMBL127573

N#CC=C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL8837099 0.87 ALDH1A1 (0.53)
SCHEMBL16866119 0.72
SCHEMBL100944 0.72
SCHEMBL243434 0.72
SCHEMBL100945 0.72
SCHEMBL862842 0.72
SCHEMBL3180032 0.67
SCHEMBL27726726 0.67
SCHEMBL3218486 0.65
SCHEMBL118543 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104059075-B 8,9-is mono-, disubstituted imidazoles [1,2-c]-quinazoline-3 (2H)-one fused heterocyclic compound and preparation method thereof ZAOZHUANG UNIVERSITY (CN) 2015-10-21 CN claimed
CN-104059075-A 8, 9-mono and/or di-substituted imidazo[1, 2-c]quinazolin-3(2H)-one fused heterocyclic compound and preparation method thereof UNIV ZAOZHUANG 2014-09-24 CN claimed
CN-103965203-A Imidazo-[1,2-c]-quinazolin-3(2H)-one fused-heterocycle compounds and preparation method thereof UNIV ZAOZHUANG 2014-08-06 CN claimed
CN-103483426-A Azacyclohexapeptide preparation method BRIGHTGENE BIO MEDICAL TECHNOOGY CO LTD 2014-01-01 CN claimed
CN-101492391-B Process for separating ethane nitrile wastewater with combination of abstraction and distillation TIANJIN PULAI CHEMICAL TECHNOLOGY CO LTD 2013-06-19 CN claimed
CN-101652356-A Stable anhydrous crystalline docetaxel and method for the preparation thereof HANMI PHARM IND CO LTD KR 2010-02-17 CN claimed
CN-101492391-A Process for separating ethane nitrile wastewater with combination of abstraction and distillation TIANJIN PULAI CHEMICAL TECHNOL (CN) 2009-07-29 CN claimed
CN-101092355-A Method for preparing antiform - 4 - acetoxy - 2 - methyl - butenoic aldehyde ZHITEQI BIOTECH CO LTD (CN) 2007-12-26 CN claimed
JP-1287073-A None JP disclosed
CN-114181179-B Compound containing naphthoquinone oxime structure and medical application of compound as bombesin receptor subtype-3 agonist 上海交通大学 2023-11-24 CN disclosed
CN-110386936-A A kind of preparation method of chloro- 7H- pyrrolo- [2,3-d] pyrimidine of 4- 新发药业有限公司 2019-10-29 CN disclosed
US-9879028-B2 Compounds that modulate EGFR activity and methods for treating or preventing conditions therewith Gatekeeper Pharmaceuticals, Inc. (US) 2018-01-30 US disclosed
CN-103228653-B The prodrug of the polycyclic carbamoylpyridone derivative be substituted SHIONOGI & CO.,LTD. (JP) 2016-03-16 CN disclosed
CN-102803260-B The polycyclic carbamoylpyridone derivative be substituted SHIONOGI & CO.,LTD. (JP) 2016-02-10 CN disclosed
EP-0339358-A1 Pyrazolopyridine type mevalonolactones NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-11-02 EP disclosed
US-4797486-A ANTIPROTOZOA AGENTS PFIZER INC. (US) 1989-01-10 US disclosed
EP-0294785-A2 Magenta dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1988-12-14 EP disclosed
US-4725599-A POULTRY PFIZER INC. (US) 1988-02-16 US disclosed
EP-0210678-A1 Novel ll-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions AKZO N.V. (NL) 1987-02-04 EP disclosed
US-4160027-A OXYTOCICS, 4A,5A-EPOXY-2A-CYANO-3-OXOSTEROIDES, STEROIDO(2,3-O)ISOOXAZOLES STERLING DRUG INC. (US) 1979-07-03 US disclosed