SCHEMBL1275798

SCHEMBL1275798

CC(C)(C)c1cc(CSCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(CSCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.47
ALDH1A1 P00352 7/20 0.42
GAA P10253 4/20 0.42
TSHR P16473 3/20 0.42
LMNA P02545 2/20 0.42
KMT2A Q03164 3/20 0.41
MAPK1 P28482 3/20 0.41
HIF1A Q16665 3/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ALOX15 P16050 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
GMNN O75496 1/20 0.41
GABBR2 O75899 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10689260 0.97 HSPA5 (0.44) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL1275492 0.86 HSPA5 (0.57) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL1275496 0.86 HSPA5 (0.49) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL1275468 0.84 HSPA5 (0.50) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL11759210 0.84 ALDH1A1 (0.53) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL9507166 0.84 ALDH1A1 (0.53) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL1275152 0.83 HSPA5 (0.56) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL10869357 0.82 GAA (0.38) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL1275477 0.82 HSPA5 (0.47) HSPA5ALDH1A1GAATSHRLMNA
SCHEMBL1274849 0.81 HSPA5 (0.48) HSPA5ALDH1A1GAATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US disclosed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
EP-0165209-B1 O,P-BIFUNCTIONALISED, O'-SUBSTITUTED PHENOLS CIBA-GEIGY AG (CH) 1989-07-19 EP disclosed
US-4759862-A O,p-bifunctionalized o'-substituted phenols CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
EP-0165209-A2 o,p-Bifunctionalised, o'-substituted phenols CIBA-GEIGY AG (CH) 1985-12-18 EP disclosed