SCHEMBL12758239

SCHEMBL12758239

CCN(/C=C/C=C1C(=O)N(C)C(=O)N(C)C1=O)CC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.43
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
RAB9A P51151 1/20 0.31
TP53 P04637 1/20 0.30
POLB P06746 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19240066 0.84 APP (0.31) APP
SCHEMBL19240062 0.81 APP (0.40) APPSMN1; SMN2TP53POLBCTDSP1
SCHEMBL19240085 0.81 APP (0.38) APPTP53
SCHEMBL9889195 0.80 APP (0.40) APPMEN1KMT2AUSP2MAPT
SCHEMBL14095048 0.79 APP (0.50) APPMEN1KMT2AMAPTCA12
SCHEMBL13855928 0.79 APP (0.50) APPMEN1KMT2AMAPTCA12
SCHEMBL9892452 0.78 KMT2A (0.41) APPMEN1KMT2AUSP2MAPT
SCHEMBL19240036 0.77 APP (0.43) APPMEN1KMT2AUSP2MAPT
SCHEMBL19240053 0.77 APP (0.40) APPMEN1KMT2AUSP2MAPT
SCHEMBL12698818 0.72 APP (0.46) APPMEN1KMT2AMAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170235032-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-17 US disclosed
US-20170235032-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-17 US disclosed
US-20110057155-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
US-20110057155-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed