SCHEMBL9892452

SCHEMBL9892452

CCOC(=O)CN(/C=C/C=C1C(=O)N(C)C(=O)N(C)C1=O)CC(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
APP P05067 3/20 0.39
USP2 O75604 1/20 0.34
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
SNCA P37840 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PIN1 Q13526 1/20 0.32
PIN4 Q9Y237 1/20 0.32
GSK3A P49840 2/20 0.32
GSK3B P49841 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889195 0.81 APP (0.40) KMT2AMEN1APPUSP2MAPT
SCHEMBL12758239 0.78 APP (0.43) KMT2AMEN1APPUSP2MAPT
SCHEMBL9892446 0.76 APP (0.39) KMT2ACRHBPCRHR2APPMAPT
SCHEMBL9892443 0.75 APP (0.40) KMT2AMEN1APPUSP2MAPT
SCHEMBL21128874 0.73 MEN1 (0.31) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL9892476 0.71 APP (0.37) CRHBPCRHR2APPMAPTCA12
SCHEMBL19240062 0.71 APP (0.40) APPSMN1; SMN2TDP1
SCHEMBL14095048 0.69 APP (0.50) KMT2AMEN1APPMAPTHTT
SCHEMBL13855928 0.69 APP (0.50) KMT2AMEN1APPMAPTHTT
SCHEMBL19240036 0.67 APP (0.43) KMT2AMEN1APPUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 KMT2A 1571/4885MEN1 48/4885CRHBP 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.