Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12759067 | 0.96 | HIF1A (0.39) | HIF1ATSHR | |
| SCHEMBL12141000 | 0.94 | HIF1A (0.35) | HIF1ATSHR | |
| SCHEMBL13660498 | 0.91 | HIF1A (0.30) | HIF1A | |
| SCHEMBL10106989 | 0.84 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL469014 | 0.82 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL12140962 | 0.82 | — | — | |
| SCHEMBL12760550 | 0.82 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL12759064 | 0.81 | TSHR (0.52) | TSHR | |
| SCHEMBL10107009 | 0.81 | TSHR (0.42) | HIF1ATSHR | |
| SCHEMBL10310587 | 0.79 | HIF1A (0.50) | HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932326-B2 | Chelating compounds and immobilized tethered chelators | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, SLC30A7, SLC39A7 | HIF1A 1825/4885TSHR 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.