Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108012 | 0.85 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3429105 | 0.84 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Fluoride SCHEMBL28254640 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9610669 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28254642 | 0.81 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4955679 | 0.81 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18927198 | 0.81 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1225128 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL24595920 | 0.80 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12623794 | 0.80 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915323-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LAMB INCORPORATED (US) | 2011-03-29 | — | — | US | disclosed |