SCHEMBL4955679

SCHEMBL4955679

C=C(C)C(=O)OCCCC(C)(C)N

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.47
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 3/20 0.37
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17865376 0.98 TSHR (0.53) TSHRTHRBTDP1POLBAPEX1
SCHEMBL28483095 0.89 TSHR (0.45) TSHRTHRBTDP1POLBAPEX1
SCHEMBL1440495 0.89 THRB (0.50) TSHRTHRBTDP1POLBAPEX1
SCHEMBL28458853 0.85 TSHR (0.45) TSHRTHRBTDP1POLBAPEX1
SCHEMBL1108012 0.85 TSHR (0.58) TSHRTHRBTDP1POLBAPEX1
SCHEMBL4631445 0.84 TSHR (0.42) TSHRTHRBTDP1POLBAPEX1
SCHEMBL24595920 0.84 TSHR (0.53) TSHRTHRBTDP1POLBAPEX1
SCHEMBL9610669 0.83 TSHR (0.56) TSHRTHRBTDP1POLBAPEX1
Fluoride SCHEMBL28254640 0.83 TSHR (0.56) TSHRTHRBTDP1POLBAPEX1
SCHEMBL18927198 0.81 TSHR (0.55) TSHRTHRBTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116600827-A Olaparib solid dispersion compositions with improved stability and bioavailability 三养控股公司 2023-08-15 CN disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
EP-2399555-B1 SUSTAINEDLY DRUG-RELEASING HYDROGEL CONTACT LENS, AND DRUG RELEASING METHOD USING SUSTAINEDLY DRUG-RELEASING HYDROGEL CONTACT LENS SEED CO LTD (JP) 2016-12-07 EP disclosed
US-8940318-B2 Hydrogel contact lens for sustained drug release and drug release method using hydrogel contact lens for sustained drug release SEED CO., LTD. (JP) 2015-01-27 US disclosed
US-7405035-B2 Pattern forming method and substance adherence pattern material FUJIFILM CORPORATION (JP) 2008-07-29 US disclosed
EP-1431821-B1 Pattern forming method and substance adherence pattern FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
EP-0878740-B1 Radiation sensitive polymer composition TORAY INDUSTRIES (JP) 2004-11-10 EP disclosed
US-20040126712-A1 Pattern forming method and substance adherence pattern material FUJI PHOTO FILM CO., LTD. 2004-07-01 US disclosed
EP-1431821-A1 Pattern forming method and substance adherence pattern FUJI PHOTO FILM CO., LTD. (JP) 2004-06-23 EP disclosed
EP-0878740-A1 Radiation sensitive polymer composition TORAY INDUSTRIES, INC. (JP) 1998-11-18 EP disclosed
EP-0299787-B1 Cloth-softening liquid composition KAO CORP (JP) 1995-03-01 EP disclosed
US-4885102-A Cloth-softening liquid composition containing quaternary ammonium compound and a polyether derivative or cationic surfactant polymer KAO CORPORATION (JP) 1989-12-05 US disclosed
EP-0299787-A2 Cloth-softening liquid composition Kao Corporation (JP) 1989-01-18 EP disclosed
EP-0076131-B1 HUMIDITY SENSOR AND METHOD FOR PREPARING A HUMIDITY SENSOR Hitachi, Ltd. (JP) 1986-04-09 EP disclosed
US-4473813-A CROSSLINKED SILICONE RESIN HITACHI, LTD. (JP) 1984-09-25 US disclosed
EP-0076131-A1 Humidity sensor and method for preparing a humidity sensor Hitachi, Ltd. (JP) 1983-04-06 EP disclosed
US-3952128-A Durable antistatic agent, hydrophobic fibers and fibrous structures having durable antistatic property and method of making same KAO SOAP CO., LTD. (JA) 1976-04-20 US disclosed