SCHEMBL1275969

SCHEMBL1275969

CCCCC(Cc1ccccc1O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.54
PTGES O14684 4/20 0.54
ALOX5 P09917 4/20 0.54
FOLH1 Q04609 3/20 0.51
MAPK1 P28482 2/20 0.49
CA2 P00918 1/20 0.49
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 1/20 0.45
AKR1B1 P15121 1/20 0.44
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
KAT8 Q9H7Z6 2/20 0.43
PPARA Q07869 1/20 0.43
EP300 Q09472 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28005647 0.84 PPARG (0.54) PPARGPTGESALOX5FOLH1MAPK1
SCHEMBL13857860 0.83 PPARG (0.50) PPARGMEN1KMT2AAKR1B1PPARA
SCHEMBL27423775 0.83 PPARG (0.53) PPARGPTGESALOX5FOLH1MAPK1
SCHEMBL10591459 0.83 PPARG (0.53) PPARGPTGESALOX5FOLH1MAPK1
SCHEMBL8904270 0.83 PPARG (0.53) PPARGPTGESALOX5FOLH1MAPK1
SCHEMBL31046596 0.83 PPARG (0.53) PPARGPTGESALOX5FOLH1MAPK1
SCHEMBL7388453 0.83 AKR1B1 (0.57) FOLH1KMT2ATSHRAKR1B1
Hydrochloric Acid SCHEMBL8719650 0.82 PPARG (0.52) PPARGPTGESALOX5FOLH1MAPK1
SCHEMBL27611086 0.82 FOLH1 (0.53) FOLH1ALDH1A1MAPTTSHRAKR1B1
SCHEMBL28268898 0.82 FOLH1 (0.53) FOLH1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057222-B1 LIQUID PHOSPHITE BLENDS AS STABILIZERS ADDIVANT SWITZERLAND GMBH (CH) 2014-03-12 EP disclosed
US-8049041-B2 Phosphite stabilizer for lubricating base stocks and thermoplastic polymers CHEMTURA CORPORATION (US) 2011-11-01 US disclosed
EP-2294074-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS Chemtura Corporation (US) 2011-03-16 EP disclosed
US-7888414-B2 Liquid phosphite blends as stabilizers CHEMTURA CORPORATION (US) 2011-02-15 US disclosed
US-20100048782-A1 Liquid phosphite blends as stabilizers SI GROUP, INC. 2010-02-25 US disclosed
US-20100016196-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS CHEMTURA CORPORATION 2010-01-21 US disclosed
US-20100004363-A1 LIQUID PHOSPHITE BLENDS AS STABILIZERS CHEMTURA CORPORATION (US) 2010-01-07 US disclosed
WO-2009158078-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS CHEMTURA CORPORATION (US) 2009-12-30 WO disclosed
EP-2057222-A2 LIQUID PHOSPHITE BLENDS AS STABILIZERS Chemtura USA Corporation (US) 2009-05-13 EP disclosed
US-20090047599-A1 NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE EASTMAN KODAK COMPANY 2009-02-19 US disclosed
WO-2007149143-A2 LIQUID PHOSPHITE BLENDS AS STABILIZERS CHEMTURA CORPORATION (US) 2007-12-27 WO disclosed
US-6919389-B2 Polymer compositions containing benzimidazole based stabilizer compounds CROMPTON CORPORATION (US) 2005-07-19 US disclosed
US-20040180995-A1 Polymer compositions containing benzimidazole based stabilizer compounds ADDIVANT USA, LLC 2004-09-16 US disclosed
US-6143814-A MAGNESIUM OR ZINC METAL CARBOXYLATE PRODUCED IN SITU CHEMSON POLYMER-ADDITIVE GESELLSCHAFT MBH (AT) 2000-11-07 US disclosed
US-4678826-A Substituted-(aminoxy)-pyrrolidine-2,5-dione stabilizers CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004363-A1 LIQUID PHOSPHITE BLENDS AS STABILIZERS PHOSPHO1, PPA1, PLCG2 PPARG 1436/4885PTGES 1004/4885ALOX5 1813/4885
US-20100016196-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS PHOSPHO1, PLCG2, PLPBP PPARG 2192/4885PTGES 472/4885ALOX5 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.