Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 6/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232438 | 0.93 | HTT (0.54) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11023778 | 0.89 | HTT (0.62) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11239030 | 0.87 | HTT (0.65) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11238943 | 0.87 | HTT (0.65) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11231700 | 0.87 | HTT (0.65) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11223752 | 0.87 | HTT (0.65) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11230752 | 0.87 | HTT (0.65) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11236320 | 0.87 | HTT (0.65) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL12886458 | 0.87 | USP2 (0.56) | HTTKDM4EUSP2CASRCYP3A4 | |
| SCHEMBL11231807 | 0.86 | KDM4E (0.52) | HTTKDM4EUSP2CASRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897716-B2 | Polyorganosiloxane compositions for the treatment of substrates | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2011-03-01 | — | — | US | disclosed |