Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123849 | 0.90 | USP2 (0.49) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL15393759 | 0.90 | USP2 (0.61) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL21019381 | 0.90 | USP2 (0.61) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL8453588 | 0.89 | USP2 (0.60) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL8578597 | 0.87 | USP2 (0.54) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL8578527 | 0.87 | USP2 (0.54) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL8575992 | 0.87 | USP2 (0.54) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL8578443 | 0.87 | USP2 (0.54) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL8578447 | 0.87 | KDM4E (0.49) | USP2HTTKDM4ELPAR5CASR | |
| SCHEMBL12761111 | 0.87 | HTT (0.51) | USP2HTTKDM4ELPAR5CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513333-B2 | Reactive surface-modified particles | MERCK PATENT GMBH (DE) | 2013-08-20 | — | — | US | disclosed |
| US-20110039990-A1 | REACTIVE SURFACE-MODIFIED PARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2011-02-17 | — | — | US | disclosed |