SCHEMBL1276157

SCHEMBL1276157

CCCCCCCCCCCCCCCCCCO[Si](O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
LPAR3 Q9UBY5 6/20 0.43
LPAR2 Q9HBW0 5/20 0.43
LPAR1 Q92633 2/20 0.43
NAAA Q02083 1/20 0.43
TSHR P16473 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CES2 O00748 1/20 0.41
GBA1 P04062 1/20 0.41
EPHX1 P07099 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2397964 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL543797 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL1157411 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL76193 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL27799298 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL28055614 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL25191483 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL28753472 0.97 THRB (0.43) THRBMEN1KMT2AHTTMAPT
SCHEMBL4809502 0.97 THRB (0.43) THRBMEN1KMT2AHTTMAPT
SCHEMBL29101281 0.97 THRB (0.43) THRBMEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106256826-A A hydrochloric acid siterizine pharmaceutical composition and its medical application 黄亦琼 2016-12-28 CN claimed
CN-106256834-A Carmustine a medicament composition thereof in biological medical use of 黄亦琼 2016-12-28 CN claimed
US-20250332119-A1 NOVEL ANTI-INFLAMMATORY COMPOSITION AND USE THEREOF ASK CO., LTD. (KR) 2025-10-30 US disclosed
CN-118702716-A Intrinsic flame-retardant organic phase change material and preparation method thereof 昆明理工大学 2024-09-27 CN disclosed
WO-2024191254-A1 LIQUID CHROMATOGRAPHY SYSTEM FOR ULTRA-DEEP PROTEOMIC ANALYSIS ㈜베르티스 2024-09-19 WO disclosed
WO-2024150964-A1 NOVEL ANTI-INFLAMMATORY COMPOSITION AND USE THEREOF 주식회사 에스크컴퍼니 2024-07-18 WO disclosed
CN-117859796-A Sweet wheat and jujube yoghourt and preparation method thereof 河南中医药大学 2024-04-12 CN disclosed
WO-2023153533-A1 COMPOSITION FOR PREVENTION AND TREATMENT OF MUSCLE DISEASE, CONTAINING MAGNOLIAE CORTEX EXTRACT AS ACTIVE INGREDIENT 트윈피그바이오랩(주) 2023-08-17 WO disclosed
CN-115380211-A Refining process and refined product 日本水产株式会社 2022-11-22 CN disclosed
CN-106353422-A Content measuring method for refreshing and pressure reducing pills 天津中新药业集团股份有限公司乐仁堂制药厂 2017-01-25 CN disclosed
CN-106256834-A Carmustine a medicament composition thereof in biological medical use of 黄亦琼 2016-12-28 CN disclosed
CN-101504394-A Content detection method for adefovir monoester FUJIAN GUANGSHENG TANG PHARMAC (CN) 2009-08-12 CN disclosed
CN-1865251-A Leucogen diastereoisomeride structural confirmation and determination method ZHANG HONGYE (CN) 2006-11-22 CN disclosed
CN-1844911-A Leech fingerprint spectrum establishment method and medicinal leech identification method LI ZHENGUO (CN) 2006-10-11 CN disclosed
CN-1844912-A Earthworm fingerprint spectrum establishment method and medicinal earthworm identification method LI ZHENGUO (CN) 2006-10-11 CN disclosed
CN-1556405-A Quality control method of chinese medicinal preparation 江苏康缘药业股份有限公司 2004-12-22 CN disclosed
US-5110960-A Tetracycline, anthracycline and anthraquinone antibiotics BRISTOL-MYERS COMPANY (US) 1992-05-05 US disclosed
EP-0277621-B1 ANTIFUNGAL ANTIBIOTICS Bristol-Myers Squibb Company (US) 1992-02-05 EP disclosed
US-4990497-A Antifungal antibiotics OKI TOSHIKAZU (JP) 1991-02-05 US disclosed
EP-0277621-A1 Antifungal antibiotics Bristol-Myers Squibb Company (US) 1988-08-10 EP disclosed