Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 4/20 | 0.69 |
| ▸ | SYK | P43405 | 9/20 | 0.61 |
| ▸ | AURKA | O14965 | 5/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | JAK3 | P52333 | 2/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1038180 | 0.99 | GLO1 (0.68) | GLO1SYKAURKAALKJAK2 | |
| SCHEMBL1035671 | 0.91 | GLO1 (0.61) | GLO1SYKALKJAK2JAK3 | |
| SCHEMBL1037220 | 0.83 | GLO1 (0.83) | GLO1SYKAURKAGSK3AAURKB | |
| SCHEMBL1039614 | 0.81 | GLO1 (0.83) | GLO1SYKAURKAALKJAK2 | |
| SCHEMBL1039144 | 0.81 | GLO1 (0.83) | GLO1SYKAURKAALKJAK2 | |
| SCHEMBL1035424 | 0.81 | GLO1 (0.78) | GLO1SYKAURKAALKJAK2 | |
| SCHEMBL1038601 | 0.81 | GLO1 (0.78) | GLO1SYKAURKAALKMAPK8 | |
| SCHEMBL1040131 | 0.80 | ALK (0.64) | GLO1ALKJAK2JAK3EGFR | |
| SCHEMBL12765469 | 0.80 | GLO1 (0.60) | GLO1SYKALKEGFRITK | |
| SCHEMBL12765437 | 0.80 | GLO1 (0.68) | GLO1SYKALKEGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098288-A1 | SULFONAMIDES AS ZAP-70 INHIBITORS | CELLZOME LIMITED (GB) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098288-A1 | SULFONAMIDES AS ZAP-70 INHIBITORS | ZAP70, SYK, LCK | GLO1 3741/4885SYK 2/4885AURKA 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.