SCHEMBL1276644

SCHEMBL1276644

Oc1ccc(-c2ccc([B-](c3ccc(-c4ccc(O)cc4)cc3)(c3c(F)c(F)c(F)c(F)c3F)c3c(F)c(F)c(F)c(F)c3F)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.46
ESR2 Q92731 6/20 0.46
MMP3 P08254 2/20 0.44
BCL2L1 Q07817 1/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KIF11 P52732 2/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
ABL1 P00519 2/20 0.38
ABCB1 P08183 2/20 0.38
BCR P11274 2/20 0.38
ALOX5 P09917 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276115 0.96 ESR1 (0.46) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL687478 0.89 ALOX15 (0.38) ESR1ESR2MMP3BCL2L1MEN1
Methylamine SCHEMBL5607731 0.83 KDM4E (0.33) ESR2MMP3BCL2L1MEN1KMT2A
Trimethylammonium SCHEMBL7941120 0.82 KDM4E (0.32) ESR2MEN1KMT2ANPC1RAB9A
SCHEMBL3670485 0.76 MEN1 (0.31) ESR1ESR2MEN1KMT2AUSP2
SCHEMBL1276667 0.75 CYP1A2 (0.42) ESR1ESR2HSD17B1HSD17B2ABL1
Allylamine SCHEMBL15251342 0.74
SCHEMBL12816913 0.73 ESR1 (0.30) ESR1ESR2
SCHEMBL1276489 0.71 CYP1A2 (0.42) ESR1ESR2HSD17B1HSD17B2ABL1
SCHEMBL21793633 0.70 CA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957167-B2 Polymerization process using a supported constrained geometry catalyst UNIVATION TECHNOLOGIES, LLC (US) 2015-02-17 US disclosed
EP-2459603-B1 POLYMERIZATION PROCESS USING A SUPPORTED CONSTRAINED GEOMETRY CATALYST UNIVATION TECH LLC (US) 2014-07-02 EP disclosed
EP-2459603-A1 POLYMERIZATION PROCESS USING A SUPPORTED CONSTRAINED GEOMETRY CATALYST Univation Technologies, LLC (US) 2012-06-06 EP disclosed
US-20120130032-A1 POLYMERIZATION PROCESS USING A SUPPORTED CONSTRAINED GEOMETRY CATALYST UNIVATION TECHNOLOGIES, LLC (US) 2012-05-24 US disclosed
WO-2011017092-A1 POLYMERIZATION PROCESS USING A SUPPORTED CONSTRAINED GEOMETRY CATALYST UNIVATION TECHNOLOGIES, LLC (US) 2011-02-10 WO disclosed
EP-0971962-B1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS BP CHEM INT LTD (GB) 2004-02-11 EP disclosed
US-6479599-B1 Catalyst system for high yield synthesis of polyolefins BP CHEMICALS LIMITED (GB) 2002-11-12 US disclosed
EP-0946601-B1 IONIC COMPOUNDS FOR CATALYST COMPONENTS, DISPERSIONS AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES INC (US) 2002-09-25 EP disclosed
US-6271165-B1 SOLID COORDINATION CATALYST THE DOW CHEMICAL COMPANY 2001-08-07 US disclosed
US-6166161-A Incorporation of functionalized comonomers in polyolefins THE DOW CHEMICAL COMPANY (US) 2000-12-26 US disclosed
EP-0946601-A1 CATALYST COMPONENT DISPERSION COMPRISING AN IONIC COMPOUND AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1999-10-06 EP disclosed
US-5783512-A Catalyst component dispersion comprising an ionic compound and solid addition polymerization catalysts containing the same THE DOW CHEMICAL COMPANY (US) 1998-07-21 US disclosed
WO-1998027119-A1 CATALYST COMPONENT DISPERSION COMPRISING AN IONIC COMPOUND AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1998-06-25 WO disclosed