SCHEMBL12768136

SCHEMBL12768136

c1ccc2c(c1)ccc1cc(-c3c4ccccc4c(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)c4ccccc34)ccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.52
PRKDC P78527 6/20 0.42
GGPS1 O95749 1/20 0.40
PTGES2 Q9H7Z7 1/20 0.37
CYP1B1 Q16678 2/20 0.36
SOS1 Q07889 1/20 0.36
CYP1A1 P04798 1/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HIF1A Q16665 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12768027 0.95 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL12768149 0.93 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL12768078 0.93 ALOX5 (0.50) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL125685 0.92 ALOX5 (0.55) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL126541 0.91 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL20127528 0.91 ALOX5 (0.51) ALOX5PRKDCGGPS1CYP1B1CYP1A1
SCHEMBL12767990 0.91 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL12768161 0.91 ALOX5 (0.50) ALOX5PRKDCGGPS1PTGES2SOS1
SCHEMBL26950482 0.90 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2CYP1B1
SCHEMBL16067514 0.90 ALOX5 (0.50) ALOX5PRKDCGGPS1CYP1B1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10461257-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices IDEMITSU KOSAN CO., LTD. (JP) 2019-10-29 US disclosed
US-20170222153-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2017-08-03 US disclosed
US-20170222153-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2017-08-03 US disclosed
US-9660195-B2 Anthracene derivative having a phenanthryl group IDEMITSU KOSAN CO., LTD. (JP) 2017-05-23 US disclosed
US-9660195-B2 Anthracene derivative having a phenanthryl group IDEMITSU KOSAN CO., LTD. (JP) 2017-05-23 US disclosed
US-8822041-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices IDEMITSU KOSAN CO., LTD. (JP) 2014-09-02 US disclosed
US-8822041-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices IDEMITSU KOSAN CO., LTD. (JP) 2014-09-02 US disclosed
US-20140103319-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2014-04-17 US disclosed
US-20140103319-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2014-04-17 US disclosed
US-20110068683-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES Idemtsu Kosan Co., Ltd 2011-03-24 US disclosed
US-20110068683-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES Idemtsu Kosan Co., Ltd 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10461257-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices ANXA7, AAAS, ANXA1 ALOX5 323/4885PRKDC 3655/4885GGPS1 781/4885
US-20170222153-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES ANXA7, AAAS, ANXA1 ALOX5 323/4885PRKDC 3655/4885GGPS1 781/4885
US-20110068683-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES ANXA7, AAAS, ANXA1 ALOX5 323/4885PRKDC 3655/4885GGPS1 781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.