Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305651 | 1.00 | MAPT (0.61) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL14305652 | 0.83 | MAPT (0.57) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL14313389 | 0.83 | MAPT (0.57) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL14305648 | 0.83 | MAPT (0.57) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL166048 | 0.81 | CYP1A1 (0.63) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL10036804 | 0.81 | CYP1A1 (0.63) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL14305644 | 0.80 | MAPT (0.54) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL14313188 | 0.80 | NPC1 (0.77) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL14313186 | 0.79 | MAPT (0.53) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL10036802 | 0.79 | CYP1A1 (0.65) | MAPTNPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097268-A1 | RADIOHALOIMATINIBS AND METHODS OF THEIR SYNTHESIS AND USE IN PET IMAGING OF CANCERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097268-A1 | RADIOHALOIMATINIBS AND METHODS OF THEIR SYNTHESIS AND USE IN PET IMAGING OF CANCERS | ROS1, HRAS, MYC | MAPT 1931/4885NPC1 1220/4885NFKB1 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.