⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17124623 | 1.00 | — | — | |
| SCHEMBL17775028 | 1.00 | — | — | |
| SCHEMBL17124624 | 1.00 | — | — | |
| SCHEMBL19078931 | 1.00 | — | — | |
| SCHEMBL767704 | 0.84 | — | — | |
| SCHEMBL20419054 | 0.82 | — | — | |
| SCHEMBL18294595 | 0.81 | FGF1 (0.33) | — | |
| SCHEMBL19051014 | 0.81 | FGF1 (0.33) | — | |
| SCHEMBL25605193 | 0.81 | FGF1 (0.33) | — | |
| SCHEMBL25594520 | 0.81 | FGF1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283496-A1 | OLIGONUCLEOTIDES FOR REDUCTION OF PD-L1 EXPRESSION | HOFFMANN-LA ROCHE INC. | 2017-10-05 | — | — | US | disclosed |
| US-20170191064-A1 | OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2017-07-06 | — | — | US | disclosed |
| US-9090649-B2 | Oligonucleotide duplexes comprising DNA-like and RNA-like nucleotides and uses thereof | PALADIN LABS, INC. (CA) | 2015-07-28 | — | — | US | disclosed |
| US-20110077286-A1 | OLIGONUCLEOTIDE DUPLEXES COMPRISING DNA-LIKE AND RNA-LIKE NUCLEOTIDES AND USES THEREOF | ENDO OPERATIONS LIMITED (IE) | 2011-03-31 | — | — | US | disclosed |