Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | NCK1 | P16333 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12991139 | 0.88 | CYP1A2 (0.68) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL20018980 | 0.86 | CYP1A2 (0.70) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL12769102 | 0.85 | ALDH1A1 (0.39) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL607927 | 0.85 | CYP1A2 (0.71) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL12990554 | 0.84 | CYP1A2 (0.62) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL597341 | 0.83 | CYP1A2 (0.67) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL598308 | 0.78 | CYP1A2 (0.60) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL20809388 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL26330826 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP2A6ALDH1A1LMNAKDM4E | |
| SCHEMBL20808993 | 0.74 | ALDH1A1 (0.61) | CYP1A2CYP2A6ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181482-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2015-11-10 | — | — | US | disclosed |
| US-20110051049-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110051049-A1 | LIQUID-CRYSTAL DISPLAY | VCL, LPXN, ACP3 | CYP1A2 4220/4885CYP2A6 3999/4885ALDH1A1 3989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.