SCHEMBL12769364

SCHEMBL12769364

CCC(=O)C1CCC(c2ccc(-c3ccc(C(C)C)cc3)cc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ FFAR1 O14842 1/20 0.48
▸ FASN P49327 1/20 0.40
▸ APP P05067 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ KIF11 P52732 1/20 0.39
▸ P2RY14 Q15391 1/20 0.39
▸ GAA P10253 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ACACB O00763 2/20 0.38
▸ ACACA Q13085 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14231794 0.83 NPC1 (0.44) NPC1RAB9AFFAR1ALDH1A1GAA
SCHEMBL14336239 0.83 NPC1 (0.53) NPC1RAB9AFFAR1ALDH1A1P2RY14
SCHEMBL10787045 0.81 SMN1; SMN2 (0.51) NPC1RAB9AFFAR1ALDH1A1KMT2A
SCHEMBL10788992 0.81 NPC1 (0.50) NPC1RAB9AFFAR1ALDH1A1KMT2A
SCHEMBL13267750 0.80 MAPT (0.51) NPC1RAB9AKMT2ACYP2C9
SCHEMBL10791755 0.79 NPC1 (0.49) NPC1RAB9AP2RY14ACACBCYP2C9
SCHEMBL10789001 0.79 NPC1 (0.49) NPC1RAB9AFFAR1ALDH1A1KMT2A
SCHEMBL10791878 0.77 SMN1; SMN2 (0.53) NPC1RAB9AFFAR1ALDH1A1GAA
SCHEMBL10787052 0.77 NPC1 (0.47) NPC1RAB9AFFAR1CYP2C9
SCHEMBL11290316 0.76 NPC1 (0.44) NPC1RAB9AALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7898625-B2 Liquid crystal device having a pair of electrodes with a vertical alignment film in which the chiral pitch length to gap ratio (P/G) is 0.06 to less than 1.0 FUJIFILM CORPORATION (JP) 2011-03-01 — — US disclosed
US-7871539-B2 Liquid crystal composition, liquid crystal element, reflective display material, light-controlling material, and method of preparing liquid crystal composition FUJIFILM CORPORATION (JP) 2011-01-18 — — US disclosed
US-7820071-B2 Light modulating material and light modulating method FUJIFILM CORPORATION (JP) 2010-10-26 — — US disclosed
US-20100227084-A1 LIQUID CRYSTAL COMPOSITION AND REFLECTIVE DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2010-09-09 — — US disclosed
US-7780870-B2 Liquid crystal composition, liquid crystal element, and siloxane polymer FUJIFILM CORPORATION (JP) 2010-08-24 — — US disclosed
US-7763883-B2 Image display device FUJIFILM CORPORATION (JP) 2010-07-27 — — US disclosed
US-7713437-B2 Liquid crystal composition, liquid crystal element, reflective display material, and light-controlling material FUJIFILM CORPORATION (JP) 2010-05-11 — — US disclosed
US-20100092784-A1 OPTICAL FILM, AND GLASS FUJIFILM CORPORATION (JP) 2010-04-15 — — US disclosed
US-20100039595-A1 LIQUID CRYSTAL DEVICE FUJIFILM CORPORATION (JP) 2010-02-18 — — US disclosed
US-20090297735-A1 LIGHT MODULATING MATERIAL AND LIGHT MODULATING METHOD FUJI-FILM CORPORATION (JP) 2009-12-03 — — US disclosed
US-20070218216-A1 Light modulating material FUJIFILM CORPORATION 2007-09-20 — — US disclosed
US-20070218216-A1 Light modulating material FUJIFILM CORPORATION 2007-09-20 — — US disclosed
US-7270857-B2 Liquid crystal composition and liquid crystal element FUJIFILM CORPORATION (JP) 2007-09-18 — — US disclosed
US-20070131903-A1 Dichroic dye and a low molecular weight gelling agent, high display performance FUJIFILM CORPORATION 2007-06-14 — — US disclosed
US-7220466-B2 Liquid crystal composition and liquid crystal device FUJIFILM CORPORATION (JP) 2007-05-22 — — US disclosed
US-20070071911-A1 pair of electrodes of which at least one is a transparent electrode and a liquid crystal layer between; liquid crystal layer contains at least two compositions of dual frequency addressable smectic liquid crystal compositions having different threshold voltages; a guest-host type liquid crystal element FUJI PHOTO FILM CO., LTD. 2007-03-29 — — US disclosed
US-20070071911-A1 pair of electrodes of which at least one is a transparent electrode and a liquid crystal layer between; liquid crystal layer contains at least two compositions of dual frequency addressable smectic liquid crystal compositions having different threshold voltages; a guest-host type liquid crystal element FUJI PHOTO FILM CO., LTD. 2007-03-29 — — US disclosed
US-20070007492-A1 Liquid crystal composition, liquid crystal element, and cross-linked siloxane polymer FUJI PHOTO FILM CO., LTD. (JP) 2007-01-11 — — US disclosed
US-20070007492-A1 Liquid crystal composition, liquid crystal element, and cross-linked siloxane polymer FUJI PHOTO FILM CO., LTD. (JP) 2007-01-11 — — US disclosed
US-20070003735-A1 Display device FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 — — US disclosed
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