Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290286 | 1.00 | NPC1 (0.44) | NPC1RAB9ACYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL11295757 | 0.89 | CYP2C9 (0.42) | NPC1RAB9ACYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL11295760 | 0.89 | CYP2C9 (0.42) | NPC1RAB9ACYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL11290197 | 0.86 | HTR7 (0.47) | NPC1RAB9ACYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL10787997 | 0.86 | HTR7 (0.47) | NPC1RAB9ACYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL1846744 | 0.85 | NPC1 (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11289965 | 0.85 | HTR7 (0.43) | NPC1RAB9ACYP2C9ALDH1A1MAPT | |
| SCHEMBL11289964 | 0.85 | HTR7 (0.43) | NPC1RAB9ACYP2C9ALDH1A1MAPT | |
| SCHEMBL10786411 | 0.84 | DPP4 (0.39) | NPC1RAB9ACYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL10786417 | 0.84 | OPRM1 (0.40) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014840-B1 | FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS | MERCK PATENT GmbH (DE) | 1982-01-06 | — | — | EP | disclosed |
| US-4302352-A | Fluorophenylcyclohexanes, the preparation thereof and their use as components of liquid crystal dielectrics | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-11-24 | — | — | US | disclosed |
| EP-0014840-A1 | Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means | MERCK PATENT GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |