Demannose

Demannose

SCHEMBL1277

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ TDP1 Q9NUW8 1/20 0.55
▸ PDE4A P27815 1/20 0.46
▸ AKR1B1 P15121 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ SLCO1B1 Q9Y6L6 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.41
▸ MPI P34949 1/20 0.35
▸ CYP2C19 P33261 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ TOP1 P11387 1/20 0.33
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL9576995 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL284703 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL94289 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL20956808 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL20500378 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL12474438 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL5070598 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL17144009 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Galactose SCHEMBL20818999 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Galactose SCHEMBL8371122 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2937220 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 — — None — — US claimed
US-9974485-B2 Method and system for providing remote healthcare services VERIZON PATENT AND LICENSING INC. (US) 2018-05-22 — — US claimed
US-9974827-B2 Vasopressin formulations for use in treatment of hypotension PAR PHARMACEUTICAL, INC. (US) 2018-05-22 — — US claimed
US-9974903-B1 System and method for providing alerts optimized for a user DEXCOM, INC. (US) 2018-05-22 — — US claimed
US-9975866-B2 Process for synthesis of furan derivative using an acid catalyst and preparation thereof DEPARTMENT OF BIOTECHNOLOGY. MINISTRY OF SCIENCE AND TECHNOLOGY, GOVERNMENT OF INDIA (IN) 2018-05-22 — — US claimed
US-9977875-B2 Systems and methods of managing treatment of a chronic condition by symptom tracking CORCEPT THERAPEUTICS, INC. (US) 2018-05-22 — — US claimed
US-9974833-B2 Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid homeostasis in a subject having pregnancy intrahepatic cholestasis NGM BIOPHARMACEUTICALS, INC. (US) 2018-05-22 — — US claimed
US-9975940-B2 Long-acting single-chain insulin analogues CASE WESTERN RESERVE UNIVERSITY (US) 2018-05-22 — — US claimed
US-9974778-B2 Substituted pyridinones as MGAT2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2018-05-22 — — US claimed
US-9974472-B2 Temperature-compensated analyte monitoring devices, systems, and methods thereof ABBOTT DIABETES CARE INC. (US) 2018-05-22 — — US claimed
US-3943171-A Method of producing acrylamide with a Raney copper catalyst NALCO CHEMICAL COMPANY (US) 1976-03-09 — — US claimed
US-3939041-A FROM DEXTROSE AND CROSSLINKED CELLS OF STREPTOMYCES CORNING GLASS WORKS (US) 1976-02-17 — — US claimed
US-3939269-A Benzenesulfon YL-semicarbazides for lowering blood sugar levels HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-17 — — US claimed
US-3936385-A PEROXY AND CHLORINE COMPOUND COLGATE-PALMOLIVE COMPANY (US) 1976-02-03 — — US claimed
US-3935068-A GLUCOSE TO FRUCTOSE, GLUCOSE ISOMERASE, POLYELECTROLYTE R. J. REYNOLDS TOBACCO COMPANY (US) 1976-01-27 — — US claimed
US-3934048-A Multifunctional sweetening composition GENERAL FOODS CORPORATION (US) 1976-01-20 — — US claimed
US-3933698-A Preparation of low friability rigid polyurethane foam OLIN CORPORATION (US) 1976-01-20 — — US claimed
US-3933593-A POLAROGRAPHIC OXYGEN ELECTRODE BECKMAN INSTRUMENTS, INC. (US) 1976-01-20 — — US claimed
US-3932619-A ANTICOCCIDIAL AGENTS, MONENSIN, GLUCOSE, ENZYMES ELI LILLY AND COMPANY (US) 1976-01-13 — — US claimed
US-3931148-A ALKALI SOLUBLE SURFACTANT BASF WYANDOTTE CORPORATION (US) 1976-01-06 — — US claimed
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