SCHEMBL12770944

SCHEMBL12770944

COc1ccc(O)c(Pc2ccccc2/C=N/c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 6/20 0.53
▸ CA1 P00915 3/20 0.51
▸ CA2 P00918 3/20 0.51
▸ MAPT P10636 4/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ ALDH1A1 P00352 4/20 0.43
▸ GAA P10253 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ MAOA P21397 1/20 0.42
▸ SIRT2 Q8IXJ6 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12770959 0.88 MAOB (0.55) MAOBCA1CA2MAPTKMT2A
SCHEMBL12770938 0.86 RAB9A (0.41) MAOBCA1CA2MAPTKMT2A
SCHEMBL12770891 0.83 MAOB (0.47) MAOBMAPTKMT2AMEN1HSD17B10
SCHEMBL12770943 0.83 MAOB (0.46) MAOBCA1CA2MAPTKMT2A
SCHEMBL14337473 0.81 MAOB (0.74) MAOBCA1CA2MAPTKMT2A
SCHEMBL12770893 0.81 SIRT2 (0.58) MAOBCA1CA2MAPTKMT2A
SCHEMBL12771182 0.80 ERN1 (0.58) CA1CA2MAPTALDH1A1LMNA
SCHEMBL12770945 0.77 MAOB (0.55) MAOBMAPTKMT2AMEN1ALDH1A1
SCHEMBL14523190 0.77 MAOB (0.47) MAOBCA1CA2MAPTKMT2A
SCHEMBL12843421 0.77 MAOB (0.47) MAOBCA1CA2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 — — US disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 — — US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 — — US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MAOB 2310/4885CA1 754/4885CA2 1200/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MAOB 2310/4885CA1 754/4885CA2 1200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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