SCHEMBL12778019

SCHEMBL12778019

[3H]OOS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1939752 0.68
SCHEMBL2465790 0.63
SCHEMBL2788464 0.58
SCHEMBL12125245 0.54
SCHEMBL620330 0.50
SCHEMBL1108067 0.47
Hydrogen Peroxide SCHEMBL797278 0.45
Water SCHEMBL1147717 0.45
Ammonia Solution, Strong SCHEMBL7066937 0.45
SCHEMBL4922010 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476034-B2 Methods and compositions for assaying homocysteine GENERAL ATOMICS (US) 2013-07-02 US disclosed
US-20120301911-A1 Rapid Detection of Molds that Produce Glucose Oxidase JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2012-11-29 US disclosed
US-20110065697-A1 2-OXY-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY NORGINE B.V. (NL) 2011-03-17 US disclosed
US-7858617-B2 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one; inhibition of a lipase, esterase or phosphatase enzyme NORGINE B.V. (NL) 2010-12-28 US disclosed
US-7776853-B2 2-amino-benzoxazinone derivatives for the treatment of obesity NORGINE B.V. (NL) 2010-08-17 US disclosed
US-20090029978-A1 THIENO-(1,3)-OXAZIN-4-ONES WITH LIPASE INHIBITING ACTIVITY ALIZYME THERAPEUTICS LIMITED (GB) 2009-01-29 US disclosed
US-7468392-B1 Anti-fatigue cyclohexenone compounds from antrodia camphorata GOLDEN BIOTECHNOLOGY CORPORATION (TW) 2008-12-23 US disclosed
US-20080312474-A1 NOVEL ANTI-FATIGUE CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA GOLDEN BIOTECHNOLOGY CORPORATION (TW) 2008-12-18 US disclosed
US-20080305507-A1 METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE GENERAL ATOMICS (US) 2008-12-11 US disclosed
US-20080241880-A1 Methods and compositions for determination of glycated proteins GENERAL ATOMICS 2008-10-02 US disclosed
US-7407954-B2 Thieno-(1,3)-oxazin-4-ones with lipase inhibiting activity ALIZYME THERAPEUTICS LIMITED (GB) 2008-08-05 US disclosed
US-20080161301-A1 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one; inhibition of a lipase, esterase or phosphatase enzyme ALIZYME THERAPEUTICS LIMITED (GB) 2008-07-03 US disclosed
US-20080070971-A1 Medical Use of Bilirubin and its Structural Analogues WANG XIANG H 2008-03-20 US disclosed