Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779780 | 0.90 | HTT (0.39) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779769 | 0.88 | GAA (0.42) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779777 | 0.86 | HTT (0.42) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779102 | 0.86 | MAPT (0.49) | HTTMAPTL3MBTL1TDP1GAA | |
| SCHEMBL12779742 | 0.86 | HTT (0.37) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779600 | 0.86 | HTT (0.37) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779821 | 0.85 | HTT (0.36) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779707 | 0.85 | MAPT (0.42) | HTTTMPRSS4MAPTL3MBTL1TDP1 | |
| SCHEMBL12779146 | 0.85 | HTT (0.42) | HTTTMPRSS4MAPTGAAMEN1 | |
| SCHEMBL12779219 | 0.84 | CCR5 (0.33) | HTTMAPTL3MBTL1PTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |