Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991464 | 0.74 | AKT1 (0.48) | PIK3CDPIK3CGPIK3CAPIK3C3PIK3CB | |
| SCHEMBL7998274 | 0.66 | AKT1 (0.49) | PIK3CDPIK3CGPIK3CAPIK3C3PIK3CB | |
| SCHEMBL12515117 | 0.65 | PIK3C3 (0.47) | PIK3CDPIK3CGPIK3CAPIK3C3PIK3CB | |
| SCHEMBL5147605 | 0.55 | KMT2A (0.93) | KMT2ALMNAMEN1USP2MAPT | |
| SCHEMBL28669004 | 0.55 | KMT2A (0.63) | KMT2ALMNAMEN1USP2MAPT | |
| SCHEMBL4144446 | 0.55 | ADORA3 (0.48) | KMT2ALMNAMEN1MAPTALOX15 | |
| SCHEMBL2802003 | 0.54 | KMT2A (0.54) | KMT2ALMNAMEN1USP2MAPT | |
| SCHEMBL4132373 | 0.54 | ADORA3 (0.47) | KMT2ALMNAMEN1MAPTNPSR1 | |
| SCHEMBL12274035 | 0.53 | PIK3CD (0.62) | PIK3CDPIK3C3KMT2AMEN1 | |
| SCHEMBL1558035 | 0.52 | CYP3A4 (0.48) | PIK3CDPIK3CGPIK3CAPIK3CBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311842-A2 | PI3K/M TOR inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2011-04-20 | — | — | EP | disclosed |